Risk factors and serological diagnosis of Helicobacter pylori infection in children with abdominal pain and vomiting
Rattachement africain : np, bd. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Helicobacter pylori is a Gram-negative bacterium that ranks among the most prevalent chronic infections around the globe. It's closely associated with conditions like gastritis, peptic ulcers, gastric cancer, and mucosa-assisted lymphoid tissue (MALT) lymphoma. Most people get infected during childhood, especially in developing nations, where factors like overcrowding, inadequate sanitation, and unsafe drinking water play a significant role. In Bangladesh, for instance, more than 60% of children are infected by the time they turn two. Getting an accurate diagnosis is essential to minimize complications and enhance the management of gastrointestinal disorders in kids. Objectives of the study were to assess prevalence, risk factors, and diagnostic accuracy of serological testing for Helicobacter pylori infection in symptomatic Bangladeshi children. Methods: This case control study was conducted at the Pediatric Gastroenterology and Nutrition Department, BSMMU, Dhaka from April 2021 to October 2022. A total of 98 children aged 1–18 years with abdominal pain and/or vomiting were enrolled by purposive sampling. Cases were defined by positive anti-H. pylori IgG serology, and controls were seronegative. Data collection included demographic, socioeconomic, clinical, and laboratory variables. Statistical analysis employed statistical package for the social sciences (SPSS) v20, with logistic regression for adjusted associations. Results: Among 96 children, 48 were H. pylori IgG positive. Significant risk factors included low socioeconomic status (50% versus 4.2%, p<0.001), low parental education (27.1% versus 0%, p<0.001), and living in a joint family (52.1% versus 14.6%, p<0.001). Key symptoms in positive patients were dyspepsia (78%), loss of appetite (64%), and pallor (66%, p<0.001). Stool antigen was positive in 82% of seropositive cases, and chronic gastritis was the predominant histological finding (92%). Conclusions: H. pylori infection is common in children with abdominal pain strongly linked to poor socioeconomic, environmental, and vomiting children.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Risk factors and serological diagnosis of Helicobacter pylori infection in children with abdominal pain and vomiting
- Date Crossref
- 25/11/2025
- Éditeur
- Medip Academy
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Nepal Medical College Teaching Hospital pays non établi dans la noticeUniversité ou école supérieure
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Bangladesh University pays non établi dans la noticeUniversité ou école supérieure
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University of Dhaka pays non établi dans la noticeUniversité ou école supérieure
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National Institute of Cardiovascular Diseases pays non établi dans la noticeOrganisme public
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National Institute of Cancer Research and Hospital pays non établi dans la noticeÉtablissement de santé
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National Institute of Neurosciences & Hospital Department of Neurology pays non établi dans la noticeÉtablissement de santé
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National Medical College and Teaching Hospital Department of Pediatric Gastroenterology pays non établi dans la noticeUniversité ou école supérieure
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Bangladesh Medical University Department of Pediatric Gastroenterology and Nutrition pays non établi dans la noticeUniversité ou école supérieure
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Kuwait Bangladesh Friendships Hospital Department of Obstetrics and Gynaecology pays non établi dans la noticeÉtablissement de santé
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National Gastro Liver Institute and Hospital pays non établi dans la noticeStructure de recherche
Nepal Medical College Teaching Hospital, Bangladesh University et University of Dhaka, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.