Best practices for first psychedelic experiences: harm reduction advice from the psychedelic community
Rattachement africain : us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This study aimed to develop a harm-reduction resource to facilitate safe and successful psychedelic experiences outside of regulated clinical and research settings. We employed a community-based approach to crowdsource practical recommendations for first-time psychedelic experiences from the psychedelic community. METHODS: We conducted an online survey with 581 individuals who reported psychedelic use (N = 581) on recommendations for people using psychedelics for the first-time, following the principles of community-based collaborative research. The survey assessed recommendations for and against specific psychedelics for first-time experiences, recommendations for and against combinations of psychedelics, and other advice for first-time experiences. Open-ended follow-up questions were included to understand participants' reasons for their recommendations. An experienced qualitative researcher and two qualitative coders analyzed responses to open-ended items. RESULTS: Most participants recommended psilocybin for first-time psychedelic experiences, approximately half recommended cannabis, and a third recommended MDMA/MDA (3,4-methylenedioxymethamphetamine/3,4-methylenedioxyamphetamine, ecstasy, molly). These substances were favored for their moderate intensity, dose-dependent effects, precise dosing, and relatively short duration of effects. Conversely, substances such as ayahuasca, DMT (N,N-dimethyltryptamine), 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine), and Salvia divinorum or salvinorin A were not recommended due to their intensity, mental and physical health risks, and safety concerns. Participants advised against mixing psychedelics with alcohol, stimulants, antidepressants, and narcotics/opiates. Additional recommendations included embracing the experience, learning about the substance and its effects, and setting intentions for the experience. CONCLUSIONS: Given the growing interest in psychedelics despite limited legal access and systematic education available, it is crucial to inform the public about practices that minimize risks. This project compiled recommendations from individuals who self-identified being experienced with psychedelics. The active involvement of the psychedelic community may enhance research quality and public trust in the findings.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Best practices for first psychedelic experiences: harm reduction advice from the psychedelic community
- Date Crossref
- 25/11/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Michigan Michigan Psychedelic Center pays non établi dans la noticeUniversité ou école supérieure
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University at Buffalo pays non établi dans la noticeUniversité ou école supérieure
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Jacobs Institute pays non établi dans la noticeOrganisation à but non lucratif
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University of Rochester pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health and Health Professions Department of Community Health and Health Behavior pays non établi dans la noticeUniversité ou école supérieure
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Jacobs School of Medicine and Biomedical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Warner School of Education and Human Development pays non établi dans la noticeUniversité ou école supérieure
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Blue Sage Health Consulting pays non établi dans la noticeInstitution
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Michigan Psychedelic Society pays non établi dans la noticeInstitution
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The Radical Well-Being Center pays non établi dans la noticeInstitution
Michigan Psychedelic Center — University of Michigan, University at Buffalo et Jacobs Institute, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.