A new technique for bedside functional residual capacity assessment: comparison with Body Plethysmography

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Background: Techniques for bedside assessment of lung volumes in mechanically-ventilated patients are limited. Measuring functional residual capacity (FRC) can help evaluate interventions such as mucus clearance, physiotherapy, and recruitment manoeuvres. We present and validate computed cardiopulmonography (CCP), a noninvasive technique to quantify lung volumes at the bedside. Aim: To compare CCP-measured FRC with body plethysmography (BPleth). Methods: Volunteers underwent spirometry, BPleth, and CCP on a single visit. Spirometry followed British Thoracic Society standards. At least 3 BPleth trials (coefficient of variation <5%) and 3 CCP tests were performed. CCP involves 2 steps: (1) laser gas spectroscopy and a precision flow sensor measure respired gas concentrations and flows; (2) these data, combined with patient characteristics, are processed by a cardiopulmonary model to yield lung volumes, including FRC. Pearson’s and intraclass correlations, Bland-Altman plots, and paired t-tests were used. Results: 14 volunteers (non-smokers; normal spirometry) participated. CCP-measured FRC showed high repeatability (ICC=0.98), and a strong correlation with BPleth (A; r=0.96; p<0.001). The FRC difference between methods was not significant (t(13)=1.73; p=0.11), amounting to 120ml (B; CCP erj;66/suppl_69/PA6304/F1 F1 F1 Conclusion: CCP is a precise, accurate alternative to BPleth for measuring FRC in mechanically-ventilated patients.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.