Primary pulmonary adenoid cystic carcinoma: surgical approch

Résumé fourni par la source

Primary adenoid cystic carcinoma of the lung is a rare and aggressive malignancy, accounting for only 0.09 to 0.2% of all bronchopulmonary cancers. Surgical resection remains the treatment of choice whenever feasible. Methods: It’s a retrospective study including patients who underwent surgery for primary adenoid cystic carcinoma of the lung between 2014 and 2024. Results: we collected 4 patients (3women/1men). The mean age was 43 years. The symptomatology was dominated by cough and dyspnea. One patient presented mild hemoptysis. Bronchoscopy revealed an endotracheal mass in two patients. The others had pulmonary condensation on computed tomography. Surgical interventions included cervicotomy (n=2), posterolateral thoracotomy (n=1), and video-assisted thoracotomy (n=1). It consisted of tracheal resection with anastomosis in 2 cases and lobectomy in 2 cases. Postoperative recovery was uneventful in all patients. Histopathological examination confirmed clear resection margins, except for one patient who had incomplete resection margins, necessitating postoperative radiotherapy. There was no mortality at 1 year. Conclusion: Primary adenoid cystic carcinoma of the lung is an uncommon malignancy. The mainstay of treatment is surgery, although it can be technically challenging due to the infiltrative nature of the tumor along the airways. Postoperative radiotherapy is recommended in cases of incomplete resection, which significantly contributes to improved long-term survival outcomes.

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