Surgical management and approaches to bilateral lung tumors in Uganda.

Résumé fourni par la source

Background: Lung cancer, a leading cause of death in Uganda, often presents bilaterally with late-stage diagnoses (III/IV) and limited surgical options due to lack of Video-Assisted Thoracic Surgery, restricting management to open techniques. Ranked Uganda’s 13th most common malignancy in 2022, advanced-stage detection necessitates optimized strategies. This study analyzes treatment patterns and survival outcomes (2022–2024) amid systemic constraints. Methods: A retrospective review of 158 histologically confirmed lung cancer cases from Ugandan tertiary centers assessed tumor histology, staging, treatment modalities, HIV coinfection, and survival using descriptive statistics and Kaplan-Meier estimates. Results: Surgical resection was rare (<5%), hindered by poor documentation, low surgical capacity, and limited perioperative support. Most patients (95%) received systemic therapy. Median age at diagnosis was 59 years, with female predominance (57%). HIV coinfection (9%) showed no mortality correlation (p=0.12). Overall mortality exceeded 60%, with median survival of 8 months; stage IV patients had 20% 1-year survival. Barriers included delayed diagnosis, limited CT access (<30% availability), and inadequate surgical infrastructure. Conclusion: Late-stage presentation and systemic resource gaps, notably imaging and perioperative deficits, restrict surgical management of bilateral lung tumors in Uganda. Aligning with Uganda’s 2023–2027 National Cancer Control Plan, prioritizing multidisciplinary care, early diagnosis, and diagnostic investments could expand eligibility for curative surgery.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.