IMPACT OF NEW POSITIVE BRONCHODILATOR TEST CRITERIA

Le résumé fourni par la source

The ERS/ATS interpretative strategies of 2005 defined a positive bronchodilator response (PBDR) as a minimum improvement of 200ml and 12% in FEV1 or FVC from baseline, primarily for asthma diagnosis. GEMA 5.3 guidelines, as new ERS/ATS 2021 criteria, included 10% improvement relative to reference values alongside the previous criteria The aim is to compare spirometries with PBDR using old and new criteria, analysing differences by sex, age, and post-bronchodilation FEV1 From 2018-2023, 25.250 spirometries were collected via telemedicine programme. After applying reproducibility and quality criteria 18.801 spirometries were analysed, categorised by PBDR based on both criteria, and compared across demographic subgroups using the Kappa index Clinical characteristics and subgroup analyses are summarised in provided tables The proportion of spirometries with PBDR under the new ERS/ATS 2021 criteria is comparable to the 2005 criteria. The new criteria are more restrictive for post-bronchodilator FEV1, except for those ≥ 75%, indicating substantial agreement. This may facilitate early diagnosis of airway pathologies, suggesting new criteria could be implemented for positive bronchodilator testing erj;66/suppl_69/PA1458/F1 F1 F1 erj;66/suppl_69/PA1458/F2 F2 F2

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.