Cerebrospinal Fluid-Based Traumatic Brain Injury Diagnostic Enabled by PanGIA Analysis System, a Novel Machine Learning Platform for Biomolecular Pattern Recognition

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Introduction: The PanGIA Analysis System (PAS) is a novel, machine learning-based approach to interrogate complex biological systems by training on bio-molecular signatures of individuals. These signatures are achieved by incubating a sample with proprietary hydrogel arrays (called Nutec Slides), designed to generate colorimetric signal from chemical analytes captured from a variety of liquid sample matrices based on their chemical and physical properties. Traumatic Brain Injury (TBI) is a leading cause of cognitive and behavioral deficits, disability, and death worldwide, as a result from mechanical forces applied to the brain during head impacts and motor vehicle crashes.

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