The bidirectional association between obstructive sleep apnea and diabetic kidney disease: systematic review and meta-analysis

Le résumé fourni par la source

Objective: This study aims to comprehensively explore the bidirectional association between obstructive sleep apnea (OSA) and diabetic kidney disease (DKD) through a systematic review and meta-analysis. Method: Systematically search for relevant literature on the association between OSA and DKD published from database inception to September 2025. Searches were performed in the Cochrane Library, PubMed, Embase, and Web of Science. Study quality was assessed with the Newcastle-Ottawa Scale (NOS). Meta-analysis, sensitivity analysis, and publication bias assessment were conducted using Review Manager 5.4, while R software was employed to calculate prediction intervals. The certainty of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) framework. Result: ) between DKD and non-DKD groups across all subgroup analyses (all P > 0.05). Conclusion: A significant bidirectional association exists between OSA and DKD, suggesting a mutual exacerbation of risks between the two conditions. These findings highlight the clinical importance of enhanced OSA screening in diabetic populations and regular renal function monitoring in OSA patients.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.