Peer Review Report For: Preferences for services in a patient’s first six months on antiretroviral therapy for HIV in South Africa and Zambia (PREFER): research protocol for a prospective observational cohort study [version 1; peer review: 2 approved with reservations]
Rattachement africain : Afrique du Sud, us, Zambie. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background For patients on HIV treatment in sub-Saharan Africa (SSA), the highest risk for loss from care consistently remains the first six months after antiretroviral (ART) initiation, when patients are not yet eligible for most existing differentiated service delivery (DSD) models. To reduce disengagement from care during this period, we must gain a comprehensive understanding of patients’ needs, concerns, resources, and preferences for service delivery during this period. The PREFER study will use a sequential mixed-methods approach to survey a sample of patients in South Africa and Zambia 0-6 months after ART initiation to develop a detailed profile of patient characteristics and needs. Protocol PREFER is an observational, prospective cohort study of adult patients on ART for ≤6 months at 12 public sector healthcare facilities in Zambia and 18 in South Africa that aims to inform the design of DSD models for the early HIV treatment period. It has four components: 1) survey of clients 0-6 months after ART initiation; 2) follow up through routinely collected medical records for <12 or <24 months after enrollment; 3) focus group discussions to explore specific issues raised in the survey; and 4) in South Africa only, collection of blood samples self-reported naïve participants to assess the prevalence of ARV metabolites indicating prior ART use. Results will include demographic and clinical characteristics of patients, self-reported HIV care histories, preferences for treatment delivery, and predictors of disengagement. Conclusions PREFER aims to understand why the early treatment period is so challenging and how service delivery can be amended to address the obstacles that lead to early disengagement from care and to distinguish the barriers encountered by naïve patients to those facing re-initiators. The information collected by PREFER will help respond to patients’ needs and design better strategies for service delivery and improve resource allocation going forward.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Peer Review Report For: Preferences for services in a patient’s first six months on antiretroviral therapy for HIV in South Africa and Zambia (PREFER): research protocol for a prospective observational cohort study [version 1; peer review: 2 approved with reservations]
- Date Crossref
- 01/11/2023
- Éditeur
- F1000 Research Ltd
- Type
- peer-review
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of the Witwatersrand University of the Witwatersrand, Afrique du Sud (code pays fourni par la source)Université ou école supérieure
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Boston University Global Health pays non établi dans la noticeUniversité ou école supérieure
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Ministry of Health MOH Zambia Lusaka, Zambie (code pays fourni par la source)Organisme public
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Centre for Infectious Disease Research in Zambia Zambie (code pays fourni par la source)Organisation à but non lucratif
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Faculty of Health Sciences Health Economics and Epidemiology Research Office Witwatersrand, Afrique du Sud (ville ou établissement reconnu, pays non nommé)Université ou école supérieure
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CHAI-Zambia Lusaka, Zambie (pays nommé dans l’affiliation)Institution
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Center for Infectious Disease Research in Zambia Lusaka, Zambie (pays nommé dans l’affiliation)Institution
University of the Witwatersrand (University of the Witwatersrand, Afrique du Sud), Global Health — Boston University et MOH Zambia — Ministry of Health (Lusaka, Zambie), avec 4 autres affiliations. Pays d’affiliation : Afrique du Sud, Zambie.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.