Design of a paper-based surface-enhanced Raman spectroscopy substrate for bacteria detection in biofluid

Le résumé fourni par la source

Colloidal metal nanoparticles are widely used in biosensing, offering varying degrees of signal enhancement when combined with techniques such as Raman spectroscopy. However, efforts to harness this effect yield inconsistent results, with a lack of reproducibility hindering the feasibility of surface-enhanced Raman spectroscopy for biomolecular characterization. To create a platform that provides consistent and significant Raman signal enhancement, this paper proposes a "one-pot" method that synthesizes gold nanoparticles directly in the presence of porous nitrocellulose membranes. This work demonstrates, as a proof-of-concept, that porous membrane paper decorated with gold nanoparticles in this manner provides a reliable Raman signal enhancement.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.