Analysis of the efficacy of UBE in the treatment of tophus deposition within the lumbar spinal canal
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Le résumé fourni par la source
RATIONALE: Lumbar intraspinal gouty tophus deposition is clinically rare, with nonspecific clinical/imaging features leading to frequent misdiagnosis. Current treatments mainly rely on open surgery, and systematic reports on Unilateral Biportal Endoscopy (UBE) application are scarce, necessitating exploration of UBE's efficacy. PATIENT CONCERNS: Seven patients (October 2023-November 2024) presented with persistent low back pain, accompanied by lower limb pain and/or numbness. Conservative treatment (urate-lowering drugs, anti-inflammatory drugs, and physical therapy) for ≥3 months was ineffective, and symptoms persisted or worsened. DIAGNOSES: Postoperative pathological examination confirmed urate crystal deposition (gold standard for gouty tophi). Preoperative computed tomography showed spinal canal soft tissue calcification, and magnetic resonance imaging revealed lumbar facet joint amorphous substance deposition, with obvious lumbar spinal stenosis and nerve root compression. INTERVENTIONS: All patients underwent UBE surgery-removing tophi, decompressing spinal/nerve root canals, placing drainage tubes, and receiving postoperative urate-lowering, anti-inflammatory, and nerve-nourishing treatments. OUTCOMES: All surgeries succeeded; VAS (8.00 ± 0.82→1.57 ± 0.54) and ODI (66.14 ± 3.93→18.29 ± 2.69) improved significantly (P < .05). No complications occurred; 3-12 months follow-up showed no tophus recurrence, and patients resumed daily activities. LESSONS: UBE has good short-term efficacy for this disease, offering a minimally invasive option, but long-term efficacy requires further observation to supplement spinal gout treatment evidence.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Analysis of the efficacy of UBE in the treatment of tophus deposition within the lumbar spinal canal
- Date Crossref
- 31/10/2025
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Guangzhou University of Chinese Medicine pays non établi dans la noticeUniversité ou école supérieure
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Guangdong Provincial Hospital of Traditional Chinese Medicine pays non établi dans la noticeÉtablissement de santé
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TCM-Intigrated Cancer Center of Southern Medical University pays non établi dans la noticeÉtablissement de santé
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Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine pays non établi dans la noticeUniversité ou école supérieure
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Guangzhou Hospital of Integrated Traditional and Western Medicine pays non établi dans la noticeÉtablissement de santé
Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine et TCM-Intigrated Cancer Center of Southern Medical University, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.