Estimation of 24-hour urinary sodium excretion using spot urine sample in the adult population in shandong, china

Le résumé fourni par la source

Abstract This study assessed the reliability of equations for estimating 24-hour urinary sodium excretion using first-time morning urine samples. In this study, a total of 2078 residents of Shandong Province in 2019 and 2024 were randomised, and three equations for estimating 24-HUNa were fitted using morning urine samples and 24-hour urine samples from 1454 participants (46.6 ± 13.4 years old), and the three equations as well as equations developed by other researchers were were validated. In the validation group, estimated 24-HUNa was significantly correlated with measured 24-HUNa values. There was no significant difference between the estimated 24-HUNa and the measured 24-HUNa for the three equations fitted in this study, whereas there was a significant difference between the estimated 24-HUNa and the measured 24-HUNa values using Kawasaki and Tanaka et al. In the Bland-Altman analyses, the agreement between measured and estimated 24-HUNa values for the six equations was more than 2500 mg / 24 hours. All equations showed a tendency to underestimate or overestimate 24-HUNa between different levels of actual 24-HUNa values, hypertension status, and age groups. None of the equations tested in this study could estimate an individual's 24-HUNa from a single SU. The SMASH equation fitted in this study was superior to those of other researchers in assessing population-level 24-HUNa excretion in Shandong Province.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.