The UF/MSK adult mesh-based computational human phantom library: applications to organ dosimetry in computed tomography
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Le résumé fourni par la source
Abstract Objective. To develop a comprehensive mesh-based computational human phantom library of adult males and females that span current US body-size distributions. The phantom library was developed jointly between the University of Florida and Memorial Sloan-Kettering Cancer Center and termed the UF/MSK Phantom Library. Approach. Adult phantoms were modeled by rescaling and systematically deforming the International Commission on Radiological Protection Publication 145 mesh-type reference computational phantoms to match heights, body mass, and CDC National Health and Nutrition Examination Survey-derived secondary anthropometric parameters. Low body-mass phantoms underwent uniform two-dimensional scaling of abdominal organs to avoid collision with subcutaneous fat. To accommodate larger body circumferences, a rigging procedure was developed to smoothly deform the limbs while maintaining anatomical realism and preserving tissue. A companion ‘arms-up’ version of the library appropriate for computed tomography (CT) dosimetry simulation was also constructed. A validated CT source term was developed for the Canon Aquilion ONE/GENESIS considering technique factors such as tube voltage, bowtie filter size, and beam collimation, and was used to compute slice-specific organ doses for a subset of library phantoms. Main results. A large library of 186 male and 171 female (357 total) phantoms was created. Standing height ranged from 150–200 cm for males and 150–195 cm for females, and total body mass ranged from 40–150 kg for males and 40–155 kg for females. Simulated CT organ doses varied smoothly with BMI for a fixed phantom height. Significance. The UF/MSK adult phantom library has been constructed with body morphometries representative of the US population. Organ doses computed for phantoms of varying body sizes demonstrate the importance having a morphometrically robust selection of computational phantoms for patient matching. While the immediate application of this library is to expand phantom selection options in MIRDct software ( www.mirdsoft.org ), the library can be further utilized in other applications including radiopharmaceutical, radiography, fluoroscopy, and radiotherapy organ dose reconstructions.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The UF/MSK adult mesh-based computational human phantom library: applications to organ dosimetry in computed tomography
- Date Crossref
- 21/11/2025
- Éditeur
- IOP Publishing
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Florida Medical Physics Graduate Program pays non établi dans la noticeUniversité ou école supérieure
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Florida College pays non établi dans la noticeUniversité ou école supérieure
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Indiana University Bloomington Department of Radiology and Imaging Sciences pays non établi dans la noticeUniversité ou école supérieure
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Indiana University – Purdue University Indianapolis pays non établi dans la noticeUniversité ou école supérieure
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The University of Texas Southwestern Medical Center Department of Radiation Oncology pays non établi dans la noticeÉtablissement de santé
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University of Chicago Department of Radiology pays non établi dans la noticeUniversité ou école supérieure
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Yonsei University Department of Radiation Convergence Engineering pays non établi dans la noticeUniversité ou école supérieure
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Memorial Sloan Kettering Cancer Center pays non établi dans la noticeÉtablissement de santé
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The University of Texas MD Anderson Cancer Center pays non établi dans la noticeÉtablissement de santé
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Medical Physics Program College of Medicine Medical Physics Program pays non établi dans la noticeUniversité ou école supérieure
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Department of Medical Physics pays non établi dans la noticeInstitution
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Dept. of Imaging Physics pays non établi dans la noticeInstitution
Medical Physics Graduate Program — University of Florida, Florida College et Department of Radiology and Imaging Sciences — Indiana University Bloomington, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.