CERG-07 CLINICAL AND HISTOLOGICAL PROFILE OF BRAIN TUMORS IN COTE D’IVOIRE: A RETROSPECTIVE REVIEW FROM A NEURO-ONCOLOGY MULTIDISCIPLINARY TEAM

Le résumé fourni par la source

Abstract Background Brain tumors in low-and middle-income countries are understudied, with limited access to diagnostic tools, treatment, and structured data systems. Since 2019, a multidisciplinary neuro-oncology team has been operating in Abidjan, Côte d’Ivoire, contributing to collaborative care and progressive data collection. Objective To describe the clinical and histopathological characteristics of brain tumors managed by our multidisciplinary team and highlight patterns of care. Methods We retrospectively reviewed 225 histologically confirmed brain tumor cases discussed in neuro-oncology staff meetings between 2019 and 2024. A structured excel-based dataset compiled demographic, clinical, imaging, histological, therapeutic, and survival data. Kaplan-Meier survival analysis was performed using R software. Results The cohort included 110 females and 115 males, with a mean age of 39.7 years (range: 1-82). Most patients (84,9%) had no health insurance, and 89.8% presented more than 3 months after symptom onset. Tumors were supratentorial in 172 cases, infratentorial in 41, sellar in 9, and pineal in 3. The most frequent histological types were meningiomas (n = 109), gliomas or glioneuronal tumors (n = 76) and medulloblastomas (n = 6). Surgery was performed in 98.7% of cases. Postoperative treatments included radiotherapy (n = 34), chemotherapy (n = 3), and concomitant chemoradiotherapy (n = 40). Median follow-up was 12 months, and the estimated overall survival remained above 75% at 20 months. Conclusion This study provides valuable insight into the clinical and histological landscape of brain tumors in Côte d’Ivoire. The high rate of diagnostic delay underscore health system challenges. Our experience also highlights the importance of clinician-led data collection and supports the need for formal national brain tumor registry to improve research, and regional and international collaborations.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.