Plant-Based Bioactive Compounds for Combating Antibiotic Resistance

Le résumé fourni par la source

Current antibiotic resistance is one of the most enduring dangers to rigorous antimicrobial stewardship. Even while medications that ‎target bacterial viability have historically delivered outstanding results, the selection pressure that different modes of action exert on the ‎bacteria leads to the production of antibiotic-resistant strains. Finding new antibiotics has been the main focus of most research and exciting ‎advancements, but the gap between the growing number of bacteria that are resistant to drugs and the decreasing number of novel medicines ‎has not yet been closed. Additionally, P. aeruginosa infections are difficult to treat because it can produce new resistance mechanisms to several antibiotic families, including aminoglycosides, fluoroquinolones, and βlactams. As one of the primary causes of nosocomial ‎infections, Pseudomonas aeruginosa can occasionally produce a serious situation in medical facilities. The pathogen can avoid the effects of ‎contemporary antibiotics thanks to its protective outer membrane and efflux pumps, which serve as essential survival tools. As a result, the ‎World Health Organization has designated P. aeruginosa as a priority pathogen because of the growing number of multidrug-resistant ‎‎(MDR) strains that urgently need new medications‎.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.