Sorbents

Le résumé fourni par la source

Abstract Sorbents, material used to adsorb solutes from blood or plasma, use hemoadsorption selectively (e.g., endotoxin) or in a broad-spectrum fashion. An example is endotoxin, a lipopolysaccharide (LPS) outer membrane molecule essential for virtually all gram-negative bacteria. It is generally considered a major causative agent in gram-negative bacteria infection-related shock state. LPS will bind to LPS binding protein and be transferred to bind to surface molecule CD14 when it enters into blood, presented in aggregate form or monomeric form. The signal of LPS combination with CD14 will be relayed by toll-like receptor to activate the nuclear factor-κB and produce multiple cytokines.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.