Association between normal systolic blood pressure maintenance and the risk of coronary artery calcification progression in asymptomatic non-diabetic and diabetic adults: a retrospective cohort study using data from the Korea initiatives on coronary artery calcification registry
Rattachement africain : kr, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Objectives To assess the association of normal systolic blood pressure maintenance (SBP maintain ) with coronary artery calcification (CAC) progression in non-diabetic and diabetic subjects at low to intermediate cardiovascular risk. Design Retrospective cohort study with a mean follow-up of 3.3 years. Setting Data from the Korea Initiatives on Coronary Artery Calcification registry were analysed. Participants 10 754 asymptomatic Korean adults (51.5±8.6 years; 84.5% male; 14.2% diabetes) were enrolled. Participants were divided into two groups: normal SBP maintain (<120 mmHg) and ≥elevated SBP maintain (≥120 mmHg) at the time of follow-up CAC scan. Main outcome measures CAC progression was defined as a difference of ≥2.5 between the square roots (√) of the baseline and follow-up coronary artery calcium score (CACS) (Δ√transformed CACS). Annualised Δ√transformed CACS was defined as Δ√transformed CACS divided by the interscan period. Results Compared with non-diabetics, the incidence of CAC progression was higher in diabetics (28.4% vs 47.3%, p<0.001) during a mean follow-up of 3.3 years. Normal SBP maintain was inversely associated with an annualised Δ√transformed CACS (β: −0.18, 95% CI: −0.25 to −0.12, p<0.001) in non-diabetics, but not in diabetics (β: −0.07, 95% CI: −0.31 to 0.19, p=0.631). After consecutive adjustments of age, sex, hypertension, dyslipidaemia, obesity, current smoking and baseline CACS, normal SBP maintain showed a lower risk of CAC progression than ≥elevated SBP maintain in non-diabetics; however, this association was not observed in patients with diabetes. Conclusions Maintaining normal systolic blood pressure was associated with a significantly attenuated CAC progression, especially in clinical conditions without established diabetes.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Association between normal systolic blood pressure maintenance and the risk of coronary artery calcification progression in asymptomatic non-diabetic and diabetic adults: a retrospective cohort study using data from the Korea initiatives on coronary artery calcification registry
- Date Crossref
- 01/10/2025
- Éditeur
- BMJ
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Chung-Ang University pays non établi dans la noticeUniversité ou école supérieure
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Seoul National University Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Seoul National University Bundang Hospital pays non établi dans la noticeÉtablissement de santé
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Samsung Medical Center pays non établi dans la noticeÉtablissement de santé
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Catholic University of Korea pays non établi dans la noticeUniversité ou école supérieure
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University Health System pays non établi dans la noticeÉtablissement de santé
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Yonsei University Health System pays non établi dans la noticeÉtablissement de santé
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Gangnam Heartscan Clinic pays non établi dans la noticeÉtablissement de santé
Chung-Ang University, Internal Medicine — Seoul National University Hospital et Seoul National University Bundang Hospital, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.