Angiotensin receptors in GtoPdb v.2025.3

Résumé fourni par la source

The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [63, 155]), which have around 30% sequence similarity. The octapeptide angiotensin II and the heptapeptide angiotensin III are endogenous ligands. The "sartan" family drugs such as losartan, candesartan, olmesartan, telmisartan, etc. are clinically used AT1 receptor blockers.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.