Using wearable EEG to examine age trends in sleep macro- and micro-architecture across adolescence

Le résumé fourni par la source

Study objectives: Adolescence is a period of distinct maturational changes in sleep characteristics. Historically, age trends in sleep physiology have been captured using laboratory-based polysomnography (PSG). However, multiple challenges associated with PSG, including logistical issues, budgetary constraints and ecological validity questions, limit large-scale use. The current study aims to address these challenges by using the Dreem3 headband to measure sleep at home and replicate well-established age-related trends in sleep physiology from late childhood through early adulthood. Methods: pipeline. We used linear mixed models to estimate age-related trends across 8 macro-architecture and 15 micro-architecture variables previously found to be associated with age, and explored age relationships in 24 additional macro- and micro-architecture variables. Results: At-home sleep studies using Dreem3 replicated established age trends in sleep macro- and micro-architecture, including decreases in percent time spent in non-rapid eye movement (NREM) stage 3 (N3%) sleep and decreases in NREM delta power with increasing age. Exploratory analysis revealed age effects in seven other variables, including decreases in integrated slow spindle activity and NREM cycle duration with increasing age. Conclusion: Sleep EEG wearables may offer an accessible way to characterize sleep physiology development in large cohorts, setting the stage for understanding how deviations from normative age patterns may put young people at risk for adverse outcomes.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.