The relationship between obesity and chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Rattachement africain : us, gb, tr, my, au, se, be, dk. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Obesity and chronic kidney disease (CKD) are complex diseases that are interlinked directly and indirectly. In October 2024, Kidney Disease: Improving Global Outcomes (KDIGO) held a Controversies Conference on the Relationship Between Obesity and CKD: Pathophysiology, Prognosis, and Management. The goals of the conference were to examine the most recent evidence regarding the epidemiology, pathophysiology, and treatment of obesity and CKD as well as to articulate priorities for research. A key conference theme was increasing the awareness of obesity-related CKD. Long-term, early-onset obesity and prolonged exposure to obesity carry the highest risk of developing CKD. Identifying early biomarkers of kidney dysfunction and refining assessment methods in the context of obesity could provide opportunities for preventing loss of kidney function. The foundation for managing obesity in CKD comprises modifications to diet, physical activity level, and behaviors related to both. However, these strategies can be unsuccessful in achieving or maintaining weight loss for a myriad of reasons. Pharmacotherapies, such as those including glucagon-like peptide-1 receptor agonists, are effective in weight reduction and have been shown to have kidney-protective and cardiovascular benefits. Metabolic and bariatric surgery has also demonstrated benefits in reducing obesity-related complications. Appropriateness and choice of management strategies will vary depending on age and comorbidities and may change over time. Patient-led goal setting is a foundation for dietary and physical activity interventions focusing on incremental, achievable changes toward healthy eating and an active lifestyle. Health care professionals require training to deliver these interventions and provide ongoing support with positive messaging using nonjudgmental, stigma-free language. Evaluating the optimal duration of therapy, long-term safety of novel pharmacotherapies, and therapies in the context of early and later stages of CKD is a key priority for research. Multidisciplinary collaboration is important both for optimizing patient care and for advancing research.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The relationship between obesity and chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
- Date Crossref
- 01/03/2026
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Children's Hospital of Philadelphia pays non établi dans la noticeOrganisme public
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Edinburgh Cancer Research pays non établi dans la noticeStructure de recherche
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Koç University Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Mayo Clinic Department of Medicine pays non établi dans la noticeÉtablissement de santé
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Mayo Clinic in Arizona pays non établi dans la noticeÉtablissement de santé
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University of Malaya pays non établi dans la noticeUniversité ou école supérieure
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Royal Brisbane and Women's Hospital pays non établi dans la noticeÉtablissement de santé
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Michael E. DeBakey VA Medical Center pays non établi dans la noticeÉtablissement de santé
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Baylor College of Medicine Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Great Ormond Street Hospital pays non établi dans la noticeÉtablissement de santé
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University College London Renal Unit pays non établi dans la noticeUniversité ou école supérieure
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Karolinska Institutet Department of Renal Medicine pays non établi dans la noticeUniversité ou école supérieure
Children's Hospital of Philadelphia, Edinburgh Cancer Research et Department of Medicine — Koç University, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.