Retatrutide improves steatohepatitis in an accelerated mouse model of diet-induced steatohepatitis with a fructose binge

Résumé fourni par la source

Female mice are more prone to liver injury due to a single fructose binge compared with male mice. The new 31-day mouse model induces robust steatohepatitis in mice and correlates with MASLD in children and adults. An intervention with retatrutide improves steatohepatitis in this novel mouse model, indicating despite its short duration, the model can be used to trial pharmacological interventions.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.