Surface-modified nanoplastics facilitate the dissemination and persistence of antibiotic resistance genes
Rattachement africain : cn, au. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Plastic pollution and antibiotic resistance are emerging environmental crises, which pose threat to human and ecology health. Although micro/nano plastics have been found to exacerbate antibiotic resistance genes (ARGs) dissemination, the impacts of differentially surface-modified nanoplastics on ARGs transformation remains unclear. In this study, transformation experiments were performed to elucidate the impacts of surface-modified polystyrene (PS) nanoplastics on ARGs transformation. Compared with pristine PS nanoplastics, carboxyl- and amino-modified PS nanoplastics (10 mg/L and 100 mg/L) significantly facilitate the ARG transformation frequency and efficiency. The direct mechanisms were attributed to alternations in cell membrane, including increased cell membrane permeability and pore formation on cell membrane, as well as overproduction of reactive oxygen species, which consequently induced the SOS response. And this was verified by the varied expression levels of related functional genes. Additionally, nanoplastics could inhibit the enzymatic degradation of plasmids, potentially contributing to the persistence of ARGs in environments. These findings suggest that the ecological risks associated with nanoplastics in promoting ARGs dissemination should not be overlooked, since the co-occurrence of ARGs and plastics is pervasive and persistent in diverse habitats.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Surface-modified nanoplastics facilitate the dissemination and persistence of antibiotic resistance genes
- Date Crossref
- 01/11/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Shandong University State Key Laboratory of Microbial Technology pays non établi dans la noticeUniversité ou école supérieure
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UNSW Sydney pays non établi dans la noticeUniversité ou école supérieure
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Shandong University of Science and Technology pays non établi dans la noticeUniversité ou école supérieure
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School of Environmental Science and Engineering pays non établi dans la noticeUniversité ou école supérieure
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School of Civil and Environmental Engineering pays non établi dans la noticeUniversité ou école supérieure
State Key Laboratory of Microbial Technology — Shandong University, UNSW Sydney et Shandong University of Science and Technology, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.