Supplementary Tables S1-S12 from Germline–Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis

Le résumé fourni par la source

The supplementary table file includes Supplementary Tables S1-S12. Descriptions of each table are as follows: - Supplementary Table 1: Study oligo sequences - Supplementary Table 2: Number of Off Targets calculated with Cas-OFFinder for the final set of guides. - Supplementary Table 3: Description of three sets of deletion editing experiements in prostate cells - Supplementary Table 4: List of study DEGs - all comparisons - Supplementary Table 5: Results of AG vs GG differential analysis (PC3 cells, single clones) - Supplementary Table 6: Results of AA vs GG differential analysis (PC3 cells, single clones) - Supplementary Table 7: Human tissue RNA-seq differential analysis for SPOPmut vs SPOPwt (AA vs AG and AG vs GG clone data DEG set) - Supplementary Table 8: GO analysis of AG vs GG DEGs - Supplementary Table 9: Sample names conversion and annotation - Supplementary Table 10: RNA sequencing statistics - Supplementary Table 11: List of antibodies used in this study - Supplementary Table 12: LC-MS/MS Steroid detection

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.