Prognostic factors affecting mortality in elderly, low body mass index, and poor performance status groups with lung cancer: analysis of the 2016 Korean Association of Lung Cancer Registry (KALC-R) database

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Background: Recent advancements in lung cancer treatment have brought about a paradigm shift that raises the possibility of treatment for populations who were previously not considered for lung cancer therapy. In light of these developments, it is necessary to reassess the treatment outcomes and feasibility of such advanced therapies in vulnerable populations. This study aims to provide real-world evidence on treatment outcomes across varying clinical conditions, with a focus on patients with frail conditions such as old age, low BMI, or reduced performance status, who are often underrepresented. Methods: This study analyzed data from the Korean Association of Lung Cancer Registry (KALC-R) cohort-the third nationwide survey, a multi-center cancer registry from 13 regional cancer centers and 38 hospitals from which significant number of registrations were made. In 2016, the KALC-R registered 2,808 patients who were newly diagnosed with lung cancer. Results: ). Conclusions: A select group of patients with vulnerable conditions, such as old age, low BMI, and poor performance status, may benefit from active anti-cancer treatment.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.