Intracholecystic papillary neoplasm in a child: A case report

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Introduction: Gallbladder (GB) cancer is a well-studied neoplasia that occurs within the mucosal lining of the gallbladder. More recently, a pre-invasive lesion of the gallbladder, known as intracholecystic papillary neoplasm (ICPN), has been described in the literature. Intracholecystic papillary neoplasm is rare in the adult population and is commonly found incidentally after cholecystectomy. In pediatric care, only one such case has previously been documented. Case Report: Our patient, an 11-year-old male with a history of immunosuppressant use for nephrotic syndrome, presented with symptoms suspicious for choledocholithiasis. He was found to have ICPN on histopathological analysis after cholecystectomy. Post-operative course was notable for biliary obstruction due to hemobilia that required endoscopic retrograde cholangiopancreatography (ERCP) with stent placement. Conclusion: Cholecystectomy and scheduled follow-up are a suitable way of preventing the progression of ICPN. Pediatric patients should also be considered for genetic testing.

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