Early Onset Mycoplasma spp. Infection After Kidney Transplantation: A Systematic Review
Rattachement africain : it, nl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: In recent years, there has been a progressive increase in the number of Mycoplasma spp. infections (MIs) reported among kidney transplant (KT) recipients. Although in these patients MIs have been associated with life-threatening complications and graft failure, specific epidemiology, clinical characteristics, diagnostic work-up, and treatment strategies remain undefined. METHODS: We performed a systematic review (PubMed, Embase, Scopus, and Cochrane) of MIs after kidney transplantation (PROSPERO ID: CRD42024520942). RESULTS: Our work summarizes 13 case reports, 7 retrospective case series, and 1 retrospective uncontrolled cohort study, published between 1970 and 2023, collectively reporting 30 episodes of MIs. Due to the scarcity of information, incidence, prevalence, and predisposing factors could not be explored. Time interval between kidney transplantation and MIs ranged between 3 and 120 days. More often, the surgical site (n = 18) or the urinary tract (n = 6) was involved, with most infections sustained by Mycoplasma hominis (n = 28). Clinical features included fever (n = 18), abdominal pain (n = 8), leukocytosis (n = 8), and elevated CRP levels (n = 6). The definitive diagnosis was obtained using microbial cultures (n = 16) or PCR method (n = 12), and the time required for identification varied from 3 to 90 days. Preferred antibiotics were tetracyclines (n = 19) and quinolones (n = 9). Overall, MIs led to 20 surgical interventions, 6 graft losses, and 2 deaths. CONCLUSION: Future research projects should consider the epidemiology of Mycoplasma spp. infection in solid organ transplant recipients.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Early Onset <i>Mycoplasma</i> spp. Infection After Kidney Transplantation: A Systematic Review
- Date Crossref
- 24/09/2025
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico General Surgery and Kidney Transplantation pays non établi dans la noticeÉtablissement de santé
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University of Messina pays non établi dans la noticeUniversité ou école supérieure
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University of Milan Department of Pathophysiology and Transplantation pays non établi dans la noticeUniversité ou école supérieure
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Zimmer Biomet (Netherlands) pays non établi dans la noticeEntreprise
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Dipartimento di Scienze Biomediche Odontoiatriche e delle Immagini Morfologiche e Funzionali pays non établi dans la noticeInstitution
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Dipartimento di Scienze Cliniche e di Comunità pays non établi dans la noticeÉtablissement de santé
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Laboratory of Medical Statistics and Biometry “Giulio A. Maccacaro” Milan Italy pays non établi dans la noticeStructure de recherche
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Laboratory of Molecular Virology pays non établi dans la noticeStructure de recherche
General Surgery and Kidney Transplantation — Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Messina et Department of Pathophysiology and Transplantation — University of Milan, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.