Bioinspired 3D-printing strategies for skeletal tissue regeneration: From natural architectures to clinical applications
Rattachement africain : ir, de. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Skeletal tissues possess complicated structures and thereby their regeneration confronts considerable challenges. The final objective of skeletal tissue engineering is the development of efficient engineered substitutes in order to promote tissue regeneration. Numerous efforts have been made to develop functional biomimetic constructs with superior functions and characteristics to create advanced biomaterials for skeletal regeneration. One of the efficient approaches for designing bioinspired materials is mimicking the microstructure and architecture of natural living organisms and applying them in developing biomaterials with relevant functionality. Moreover, bioinspired complex structures which are developed by mimicking natural or synthetic architectures provide a crucial role in tissue engineering. Since the traditional approaches can not fulfill the demands to design intricate biomimetic materials, employing novel technologies may be satisfying. 3D bioprinting is a rapidly evolving technology which offers accurate multi-material and multi-scale manufacturing of biomimetic constructs for the patient-specific tissue regeneration. Numerous attempts such as mimicking the hierarchical structure and function of bone tissue, resembling the zonal architecture of cartilage tissue and imitating the microstructure and mechanical characteristics of natural osteochondral tissue, can suggest clinically desirable candidates for skeletal reconstruction. Here, 3D bioprinting technology for creating bioinspired constructs for use in skeletal tissue regeneration is discussed. We review various types of bioinspired constructs developed by mimicking the endogenous structure and function of skeletal tissues. Next, biomimetic constructs that are designed by imitating other natural and synthetic structures are discussed. Clinical trials utilizing 3D-printed constructs for skeletal tissue regeneration is discussed as the final part of the story. Different strategies such as mimicking strong adhesion to different surfaces, imitating the morphology of different architectures and resembling the hierarchical structure of natural and synthetic structures can expand the opportunity to develop realistic and effective constructs for clinical regeneration of skeletal tissue.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Bioinspired 3D-printing strategies for skeletal tissue regeneration: From natural architectures to clinical applications
- Date Crossref
- 24/09/2025
- Éditeur
- SAGE Publications
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Royan Institute pays non établi dans la noticeOrganisation à but non lucratif
-
Academic Center for Education pays non établi dans la noticeOrganisation à but non lucratif
-
Amol University of Special Modern Technologies pays non établi dans la noticeUniversité ou école supérieure
-
University Hospital Ulm pays non établi dans la noticeÉtablissement de santé
-
University of Science and Culture pays non établi dans la noticeUniversité ou école supérieure
-
Qom University of Medical Science and Health Services pays non établi dans la noticeUniversité ou école supérieure
-
Cell Science Research Center Department of Cell Engineering pays non établi dans la noticeStructure de recherche
-
College of Biotechnology Department of Stem Cells and Cancer pays non établi dans la noticeUniversité ou école supérieure
-
Ulm University Hospital Institute of Molecular Oncology and Stem Cell Biology (IMOS) pays non établi dans la noticeUniversité ou école supérieure
-
Faculty of Biological Science and Technology Department of Cell and Molecular Biology Science pays non établi dans la noticeUniversité ou école supérieure
-
Qom University of Medical Sciences Cellular and Molecular Research Center pays non établi dans la noticeUniversité ou école supérieure
Royan Institute, Academic Center for Education et Amol University of Special Modern Technologies, avec 8 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.