Corrigendum to “The synergy between miR-486–5p and tamoxifen causes profound cell death of tamoxifen-resistant breast cancer cells” [Biomedicine & Pharmacotherapy141 (2021) 111925]
Rattachement africain : ir, dk, au, gb, cn. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
The authors regret an error identified in Fig. 8, titled “Combination treatment of miR-486–5p and tamoxifen decreases cancer stem cell (CD24-/CD44+) population in both non-resistant and tamoxifen-resistant BC cells.” In the originally published figure, incorrect representative images were included due to an inadvertent selection error during the figure preparation process. This mistake was entirely accidental and occurred during the assembly of multiple panels in the one image, where the wrong set was unintentionally selected for final inclusion. In the original result text, we wrote” Cancer stem cell population CD24-/CD44+ decreased in combined treatment in both non-resistant and resistant cells (P < 0.05). Besides the population of CD24-/CD44+ significantly was increased in combination treatments(P < 0.05)”, however, the correct wording should be “Both MCF-7 and TR-MCF-7 cells initially predominantly expressed CD24-/CD44+. Following treatment with either Tamoxifen or miR-486, the majority of cells differentiated into CD24-/CD44+ or CD24-/CD44+ cells. Combined treatment with Tamoxifen and miR-486 resulted in a slight increase in the proportion of CD24-/CD44+ cells compared to Tamoxifen treatment. In TR-MCF-7 cells, treatment with miR-486, resulted in an increased proportion of CD24-/CD44+ cells, along with a smaller shift towards CD24-/CD44+ cells compared to Tamoxifen treatment (P < 0.05). Additionally, in the combination of miR-486 and Tamoxifen, more cells differentiated into CD24-/CD44+, indicating a transition towards a more differentiated state.” In the original figure caption, we wrote however, the revised wording should be “miR-486–5p treatment enhances differentiation in tamoxifen-resistant breast cancer. It increases the proportion of CD24-/CD44+ cells, induces a smaller shift towards CD24-/CD44+ cells, and reduced CD24-/CD44+ cells (*P < 0.05).” And in the original discussion text, we wrote ”We show that the co-treatment of miR-486–5p and tamoxifen decreases the BC stem cell phenotype, as evidenced by reduced sizes and numbers of mammospheres, colonies and cancer stem cell population CD24-/CD44+ and increase CD24-/CD44+ population.”, The correct wording should be “We show that the co-treatment of miR-486–5p and tamoxifen decreases the BC stem cell phenotype, as evidenced by reduced sizes and numbers of mammospheres, colonies and cancer stem cell population CD24-/CD44+ and increased CD24-/CD44+ and CD24-/CD44+ population.”
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Corrigendum to “The synergy between miR-486–5p and tamoxifen causes profound cell death of tamoxifen-resistant breast cancer cells” [Biomedicine & Pharmacotherapy141 (2021) 111925]
- Date Crossref
- 01/11/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Tarbiat Modares University pays non établi dans la noticeUniversité ou école supérieure
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Tabriz University of Medical Sciences Student Research Committee pays non établi dans la noticeUniversité ou école supérieure
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University of Southern Denmark Department of Cancer and Inflammation Research pays non établi dans la noticeUniversité ou école supérieure
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Kharazmi University pays non établi dans la noticeUniversité ou école supérieure
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Islamic Azad University of Zanjan pays non établi dans la noticeUniversité ou école supérieure
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Urmia University of Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Queensland University of Technology pays non établi dans la noticeUniversité ou école supérieure
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Tarbiat Modares University, Student Research Committee — Tabriz University of Medical Sciences et Department of Cancer and Inflammation Research — University of Southern Denmark, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.