Spatio-Temporal Ganglionic Eminence MRI Atlas

Le résumé fourni par la source

Motivation: Characterize Ganglionic Eminence (GE) development during pregnancy to better understand derailments from typical trajectory that can potentially play a role in future clinical conditions. Goal(s): Construct a spatio-temporal MRI atlas of the GE during pregnancy. Approach: We extended up to 19 weeks the T2w dHCP atlas, generating a label map of the GE from the segmentations performed by 3 expert neuroradiologists. Results: The GE reached its maximum volume at 21-weeks, followed by a pronounced decrease throughout the pregnancy (R2 = 0.96). Neuroradiology experts show strong agreement in the segmentation task, achieving an average dice score of 0.91. Impact: The spatio-temporal fetal MRI atlas of the GE allows researchers to study potential future clinical conditions attributable to GE alterations in pregnancy. The GE reached its maximum expansion at 21 weeks, followed by a pronounced reduction throughout the pregnancy.

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