The TwinsUK MR Imaging study protocol: Brain and spine at 3T and cardiac plus whole-body at 0.55T

Résumé fourni par la source

Motivation: TwinsUK hosts 30 years of biological data, linked with imaging this can be used to understand how lifestyle, environment and infection exposures influence organ-specific ageing and disease. Goal(s): To develop MRI protocols at 0.55T and 3T covering the whole body, and specifically the brain, heart and liver. Approach: A protocol, consisting of two ~45 minute sessions, was developed that was inspired by the UK Biobank but optimised to suit technological advancements, and an ultra-wide bore low-field system. Results: Data collection is underway with >300 participants scanned so far and ~2500 participants to be scanned over five years. Dedicated analysis pipelines are under development. Impact: This study will generate a comprehensive MRI resource in a twin cohort of ~2500 participants. Combined with biological data, this facilitates the study of ageing and has potential to lead to more personalised approaches to managing health as we age.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.