Half a century of cancer transition in Hungary: A visualization and assessment of mortality dynamics in the Lexis diagram, 1970–2020
Rattachement africain : hu, fr. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
OBJECTIVES: Hungary is among the countries with the highest cancer mortality burden in Europe, consequently there is a crucial need to monitor changes in death rates in the population using appropriate surveillance tools. The Lexis diagram provides a means to depict age, period and cohort influences on long-term cancer mortality trends. METHODS: Age-specific mortality rates for six cancer localizations were constructed based on the Deaths Register of the Hungarian Central Statistical Office and the Human Mortality Database, then smoothed (p-splines) within the cells of the Lexis diagram assuming Poisson distribution. After calculating the annual percentage change in mortality rates, the results were visualized using heat maps. RESULTS: Substantial reduction in mortality was observable from the mid-1990s in both sexes as a strong period effect, depicting two distinct epidemiological eras in Hungary. Since 2010, breast cancer mortality in women among ages 70-90 (those born between 1930 and 1950) has been rising. Women born between 1940 and 50 experienced two plateaus in lung cancer mortality, unlike men, emphasizing the delayed nature of the smoking epidemic. CONCLUSIONS: The results align with cancer transition patterns observed in similarly developed countries and emphasize a critical need to expand the implementation of effective primary and secondary prevention measures. This includes sustaining organized screening and anti-smoking programs, as well as introducing lung cancer screening with low-dose CT.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Half a century of cancer transition in Hungary: A visualization and assessment of mortality dynamics in the Lexis diagram, 1970–2020
- Date Crossref
- 01/12/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Institute of Oncology pays non établi dans la noticeÉtablissement de santé
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Centre international de recherche sur le cancer pays non établi dans la noticeOrganisme public
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HUN-REN Centre for Agricultural Research pays non établi dans la noticeStructure de recherche
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Hungarian Central Statistical Office pays non établi dans la noticeEntreprise
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Semmelweis University National Institute of Oncology and National Tumor Biology Laboratory pays non établi dans la noticeUniversité ou école supérieure
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International Agency for Research on Cancer Cancer Surveillance Branch pays non établi dans la noticeOrganisme public
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Institute for Soil Sciences pays non établi dans la noticeStructure de recherche
National Institute of Oncology, Centre international de recherche sur le cancer et HUN-REN Centre for Agricultural Research, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.