Immunogenetic diversity and haemosporidian parasitization in European bluethroats ( Luscinia svecica ): do diverse genes warrant fewer parasites?
Rattachement africain : cz, sk, lv, no. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Abstract The health and fitness of vertebrates are constantly challenged by environmental stresses, which include exposure to diseases that pose significant evolutionary pressures on immune genes. The bluethroat ( Luscinia svecica ), has been extensively studied for its haemosporidian parasite diversity across Europe showing a high diversity and prevalence rate. Given possible evolutionary pressure exerted by these pathogens, the present study used high-throughput amplicon sequencing to explore the genetic diversity and selection mechanisms of three immunity genes (MHC I exon 3, TLR3 and TLR4) in three European bluethroat populations. Specifically, we seek to (1) characterize the genetic diversity of these immunity genes, (2) detect selection signatures shaping their diversity, and (3) investigate the relationship between these immunity genes and haemosporidian parasites ( Plasmodium and Leucocytozoon ). Selection analysis was conducted using FUBAR and SLAC methods, whereas GLM regression was employed to explore the correlation between MHC genes and haemosporidian parasites. Despite geographical and ecological differences, nucleotide and haplotype diversities were similar across all populations. Most frequent haplotypes were found to be shared by both red-spotted ( L. s. svecica ) and white-spotted ( L. s. cyanecula ) bluethroat subspecies. The “insular” Krkonoše population, despite being biogeographically peripheral and experiencing minor inbreeding, did not show significantly reduced immunogenetic diversity. Selection analysis revealed a higher presence of purifying selection in TLR genes and a combination of purifying and diversifying selection in the MHC gene, reflecting their evolutionary constraints and functional importance, while haemosporidian parasite pressure was not a major driver of genetic diversity.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Immunogenetic diversity and haemosporidian parasitization in European bluethroats ( <i>Luscinia svecica</i> ): do diverse genes warrant fewer parasites?
- Date Crossref
- 07/09/2025
- Éditeur
- openRxiv
- Type
- posted-content
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of South Bohemia in České Budějovice pays non établi dans la noticeUniversité ou école supérieure
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Institute of Parasitology of the Slovak Academy of Sciences pays non établi dans la noticeStructure de recherche
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Czech Academy of Sciences pays non établi dans la noticeStructure de recherche
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Institute of Parasitology pays non établi dans la noticeStructure de recherche
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Nature Conservation Agency Orlicke hory Protected Landscape Area Administration pays non établi dans la noticeOrganisme public
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Bioinova (Czechia) pays non établi dans la noticeEntreprise
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University of Oslo Natural History Museum pays non établi dans la noticeUniversité ou école supérieure
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Norsk Teknisk Museum pays non établi dans la noticeInstitution
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Faculty of Science pays non établi dans la noticeUniversité ou école supérieure
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Malinová 1650/27 pays non établi dans la noticeInstitution
University of South Bohemia in České Budějovice, Institute of Parasitology of the Slovak Academy of Sciences et Czech Academy of Sciences, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.