Air pollution and long COVID: association with pulmonary function and radiological abnormalities 3–15 months post-COVID
Rattachement africain : nl, ca. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
While studies have examined associations between air pollution and subjective long COVID outcomes such as fatigue and symptoms, no studies have focused on objective lung health measures. This study aimed to assess the impact of air pollution, examined through different exposure methods (exposures assigned via geospatial model, versus residential and personal measurements) on pulmonary function and radiological abnormalities in long COVID patients. We recruited 95 patients who attended a hospital outpatient clinic 3-6 months post-infection, during which pulmonary function was assessed via spirometry (FEV1,FVC,FEV1/FVC ratio) and diffusion capacity for carbon monoxide (DLCO), along with a chest CT. Of these, 38 patients with abnormalities in one of the assessed modalities returned for a follow-up visit approximately nine months later. Ambient levels of PM 2.5 , PM 10 , NO 2 , and O 3 was assigned using land-use regression models, while residential and personal PM 2.5 measurements were collected between the hospital visits in the participants' home environments. No associations were found between residential (assigned or measured) air pollution exposure and pulmonary function or radiological abnormalities at the first visit. Pulmonary function also typically improved between the first and second visit. However, an association between personal exposure and CT abnormalities was observed. A one IQR(12.3 μg/m 3 ) increase in personal PM 2.5 significantly increased the risk of airway abnormalities during the follow-up visit (adjusted OR:3.35, 95%CI:1.03,14.63), particularly mosaic patterns (OR:5.74, 95%CI:1.43,40.62). These findings add to evidence of exposure to air pollution playing a role in long COVID and call for mitigation measures to improve air quality.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Air pollution and long COVID: association with pulmonary function and radiological abnormalities 3–15 months post-COVID
- Date Crossref
- 01/12/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Utrecht University Department of Environmental Epidemiology pays non établi dans la noticeUniversité ou école supérieure
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Amsterdam Neuroscience pays non établi dans la noticeStructure de recherche
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Public Health Service of Amsterdam pays non établi dans la noticeÉtablissement de santé
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Institute of Infection and Immunity pays non établi dans la noticeStructure de recherche
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University Medical Center Utrecht Department of Radiology pays non établi dans la noticeÉtablissement de santé
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Amsterdam University Medical Centers pays non établi dans la noticeÉtablissement de santé
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University Medical Center Groningen Department of Genetics pays non établi dans la noticeÉtablissement de santé
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Amsterdam Institute for Infection and Immunity the Netherlands pays non établi dans la noticeStructure de recherche
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Dept. of Pulmonary Medicine pays non établi dans la noticeInstitution
Department of Environmental Epidemiology — Utrecht University, Amsterdam Neuroscience et Public Health Service of Amsterdam, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.