Dynamically grading cerebral collateral circulation using 3D multi-inversion time arterial spin labeling in ischemic stroke: a comparison with digital subtraction angiography
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Le résumé fourni par la source
Objective This study aims to introduce a novel non-invasive imaging method, 3D multi-inversion time arterial spin labeling (3D mTI-ASL), for grading collateral circulation in patients with acute ischemic stroke (AIS) and to compare its effectiveness with digital subtraction angiography (DSA). Methods We analyzed data from 28 patients with unilateral internal carotid artery or middle cerebral artery occlusion who underwent both DSA and 3D mTI-ASL imaging before endovascular treatment. A post-processing pipeline was established to grade collateral flow based on 16 perfusion-weighted images. The agreement between the collateral grades derived from ASL and DSA was evaluated. Results Strong interobserver agreement was observed for both DSA (κ = 0.856) and mTI-ASL (κ = 0.849). A moderate level of consistency in collateral grading between 3D mTI-ASL and DSA was noted (κ = 0.568, p < 0.001). This was improved when patients were categorized into poor and good collateral groups within both grading systems (k = 0.781, p < 0.001). Notably, patients with good collaterals (Grades 3–4) had significantly lower admission National Institutes of Health Stroke Scale scores compared to patients with poor collaterals (p < 0.028 for DSA and p < 0.015 for mTI-ASL). Conclusion The 3D mTI-ASL technique shows promise as a reliable, non-invasive method for assessing collateral circulation in AIS. By simulating DSA-derived grading, it may serve as a complementary tool in clinical decision-making for acute stroke management.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Dynamically grading cerebral collateral circulation using 3D multi-inversion time arterial spin labeling in ischemic stroke: a comparison with digital subtraction angiography
- Date Crossref
- 29/08/2025
- Éditeur
- Frontiers Media SA
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Tianjin Huanhu Hospital Department of Radiology pays non établi dans la noticeÉtablissement de santé
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Jinan Central Hospital pays non établi dans la noticeÉtablissement de santé
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Shandong First Medical University Department of Radiology pays non établi dans la noticeUniversité ou école supérieure
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Zhangqiu City People's Hospital pays non établi dans la noticeÉtablissement de santé
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Siemens (China) pays non établi dans la noticeEntreprise
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Siemens Healthineers (Germany) pays non établi dans la noticeEntreprise
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Zhangqiu District People's Hospital Department of Radiology pays non établi dans la noticeÉtablissement de santé
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Siemens Healthcare Ltd. MR Collaboration pays non établi dans la noticeEntreprise
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Siemens Healthcare GmbH MR Application Development pays non établi dans la noticeEntreprise
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Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases pays non établi dans la noticeStructure de recherche
Department of Radiology — Tianjin Huanhu Hospital, Jinan Central Hospital et Department of Radiology — Shandong First Medical University, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.