Hepatitis B Virus Care Cascade in Rwanda: A Population-based Study From 2016–2023
Rattachement africain : ca, Rwanda. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
INTRODUCTION: In sub-Saharan Africa, data on the hepatitis B virus (HBV) care cascade are limited. We assessed Rwanda's HBV care cascade. METHODS: We analyzed data from the District Health Information System 2, capturing 4.6 million individuals (≥2 years) screened for HBV from January 2016 to June 2023. The HBV care cascade included 6 stages: (1) chronic HBV prevalence, (2) diagnosis, (3) care enrollment, (4) treatment eligibility, (5) treatment initiation, and (6) treatment continuation. HBV infection was defined as a reactive hepatitis B surface antigen test. Hierarchical logistic regression identified factors influencing progression through the cascade. FINDINGS: Among 4 604 468 screened individuals, 138 512 were hepatitis B surface antigen-positive. District Health Information System 2 data included 57 520 cases, of which 52 827 (91.8%) had HBV monoinfection. Of those diagnosed, 21 247 (37.0%) were enrolled in care and 6429 (30.3%) were eligible for treatment. Among eligible individuals, 4893 (76.1%) initiated treatment, with 4839 (98.9%) retained on treatment 1-year after initiation. Individuals aged 35-54 years were more likely to engage in care (adjusted odds ratio [aOR]: 1.19; 95% confidence interval [CI]: 1.12-1.27), initiate treatment (aOR: 1.45; 95% CI: 1.14-1.86), and remain on treatment (aOR: 2.88; 95% CI: 1.09-7.63) compared to those <35 years. Individuals living 30-60 minutes from health facilities were less likely to engage in care or continue treatment compared to those living at a shorter distance. CONCLUSIONS: Engagement in the HBV care cascade is low, particularly among younger individuals and those living farther from health facilities. Efforts to improve awareness and accessibility are essential to strengthen HBV prevention and care.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Hepatitis B Virus Care Cascade in Rwanda: A Population-based Study From 2016–2023
- Date Crossref
- 29/08/2025
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
University of British Columbia British Columbia pays non établi dans la noticeUniversité ou école supérieure
-
BC Centre for Disease Control pays non établi dans la noticeOrganisme public
-
Rwanda Biomedical Center Rwanda (code pays fourni par la source)Établissement de santé
-
Vancouver Hospital and Health Sciences Centre pays non établi dans la noticeÉtablissement de santé
-
Providence Health Care pays non établi dans la noticeÉtablissement de santé
-
Data & Analytic Services pays non établi dans la noticeInstitution
-
Institute of HIV/AIDS Disease Prevention and Control Department Kigali, Rwanda (pays nommé en fin d’affiliation)Structure de recherche
-
School of Population and Public Health pays non établi dans la noticeUniversité ou école supérieure
-
Centre for Advancing Health Outcomes pays non établi dans la noticeInstitution
British Columbia — University of British Columbia, BC Centre for Disease Control et Rwanda Biomedical Center (Rwanda), avec 6 autres affiliations. Pays d’affiliation : Rwanda.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.