Risk Factors and Outcomes in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Rattachement africain : pk. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Introduction Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common cause of hospitalization and is associated with significant morbidity, mortality, and healthcare burden. Objectives To determine the risk factors and in-hospital outcomes in patients admitted with acute exacerbation of COPD. Methodology This retrospective analysis was conducted at Mayo Hospital, Lahore, Pakistan, from January 2022 to January 2025. A total of 355 patients were enrolled using a non-probability consecutive sampling technique. Demographic details (age, gender, smoking status, residence), clinical history (duration of COPD, previous exacerbations, comorbidities such as diabetes and hypertension), presenting symptoms, and initial investigations, including arterial blood gases, complete blood count, chest X-ray, and C-reactive protein, were recorded. Results The mean age of patients was 64.8 ± 9.5 years, with a male predominance of 226(63.7%). A majority, 271(76.3%), were chronic smokers. Common comorbidities included hypertension 148(41.7%), diabetes mellitus 104(29.3%), and ischemic heart disease (IHD) 47(13.2%). Non-invasive ventilation was required in 137(38.6%) of cases, while 48(13.5%) needed invasive mechanical ventilation. ICU admission was required in 67(18.9%) of patients. In-hospital mortality occurred in 34(9.5%) of patients. Significant predictors of poor outcomes included older age (>70 years), IHD, high baseline dyspnea score, and requirement for mechanical ventilation (p < 0.05). Conclusion AECOPD leads to high hospitalization and mortality rates, particularly among elderly patients and those with comorbidities like IHD and diabetes. Identifying modifiable risk factors can help improve survival and reduce complications in these patients.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Risk Factors and Outcomes in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Date Crossref
- 25/08/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Mayo Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Allama Iqbal Medical College pays non établi dans la noticeUniversité ou école supérieure
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Khyber Medical College pays non établi dans la noticeÉtablissement de santé
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Shaikh Zayed Medical College and Hospital pays non établi dans la noticeÉtablissement de santé
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Shalamar Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Allama Iqbal Teaching Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Peshawar Medical College Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Sheikh Zayed Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
Internal Medicine — Mayo Hospital, Allama Iqbal Medical College et Khyber Medical College, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.