Risk factors for prolonged hospitalization in acute decompensated heart failure from the HEROES study
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Le résumé fourni par la source
This study, part of the HEROES project (HEart failure Risk factOrs and patiEnt Stratification), aimed to identify clinical, laboratory, functional, and treatment-related factors associated with hospitalization duration (above and below 8 days) in patients admitted for acute decompensated heart failure (ADHF). We analyzed 562 Caucasian patients hospitalized due to acute decompensated heart failure (ADHF), divided into two groups based on length of stay (LOS): ≤ 8 days (n = 287; 51.07%) and > 8 days (n = 275; 48.93%). In the ≤ 8 days group, 203 patients (70.73%) were male, while in the > 8 days group, 202 patients (73.45%) were male. Data on sociodemographic features, clinical characteristics, laboratory and imaging findings, treatment details, and patient-reported health status (KCCQ-12) were collected. Multivariate logistic regression identified independent predictors of prolonged hospitalization. Patients with longer LOS had higher NYHA class (p < 0.001), greater comorbidity burden (p = 0.0019), longer intensive cardiac care unit (ICCU) stay (p < 0.001), and higher in-hospital mortality (p = 0.0006). They also showed elevated NT-proBNP (p < 0.0001), procalcitonin (p = 0.03), and creatinine (p = 0.0002), and lower hemoglobin (p = 0.004), hematocrit (p = 0.014), and sodium (p = 0.0325). In the multivariate analysis, independent predictors of prolonged hospitalization included treatment with norepinephrine (OR = 18.41), dopamine (OR = 8.62), and oral iron therapy (OR = 3.25). Conversely, protective factors associated with a reduced risk of prolonged hospitalization were higher KCCQ-12 scores (OR = 0.98), higher systolic blood pressure at admission (OR = 0.99), and prior statin use (OR = 0.56). In the HEROES study, prolonged hospitalization among ADHF patients was associated with more severe symptoms of heart failure decompensation higher comorbidity load, impaired functional and laboratory parameters and need for longer stay in ICCU. Early identification of high-risk patients may facilitate personalized management and optimize healthcare resource utilization.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Risk factors for prolonged hospitalization in acute decompensated heart failure from the HEROES study
- Date Crossref
- 09/08/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Poznan University of Medical Sciences Chair of Cardiology pays non établi dans la noticeUniversité ou école supérieure
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Medical University of Lodz Department of Internal Diseases and Clinical Pharmacology pays non établi dans la noticeUniversité ou école supérieure
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Medical University of Warsaw First Department of Cardiology pays non établi dans la noticeUniversité ou école supérieure
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Wojskowy Instytut Medycyny Lotniczej pays non établi dans la noticeStructure de recherche
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Institute of Cardiology pays non établi dans la noticeStructure de recherche
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Jan Kochanowski University Collegium Medicum pays non établi dans la noticeUniversité ou école supérieure
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John Paul II Hospital pays non établi dans la noticeÉtablissement de santé
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Gdańsk Medical University pays non établi dans la noticeUniversité ou école supérieure
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Wroclaw Medical University Institute of Heart Diseases pays non établi dans la noticeUniversité ou école supérieure
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Central Clinical Hospital pays non établi dans la noticeÉtablissement de santé
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Military Institute of Medicine - National Research Institute Department of Cardiology and Internal Diseases pays non établi dans la noticeStructure de recherche
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Swietokrzyskie Cardiology Center pays non établi dans la noticeInstitution
Chair of Cardiology — Poznan University of Medical Sciences, Department of Internal Diseases and Clinical Pharmacology — Medical University of Lodz et First Department of Cardiology — Medical University of Warsaw, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.