Clinical impact of obesity on thyroidectomy outcomes: A systematic review and meta-analysis
Rattachement africain : ie, us, cy, gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background The global prevalence of obesity is on the rise, and evaluating the interplay between obesity and outcomes in thyroid surgery is increasingly important. This meta-analysis aims to investigate the safety of thyroidectomy in patients with obesity. Methods PubMed, Ovid Embase, Cochrane Library, CINAHL, Scopus, and Web of Science were searched from its inception to February 2025 by independent reviewers using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The review was registered prospectively on the PROSPERO database (CRD42025630687). Results Ten studies, including 108,153 patients, met eligibility criteria, with 23,754 (22%) classified as having obesity. Patients with obesity had greater risks of experiencing recurrent laryngeal nerve injury (odds ratio, 1.15; 95% confidence interval, 1.04–1.28, I 2 = 7%), hematoma (odds ratio, 1.18; 95% confidence interval, 1.02–1.36, I 2 = 0%), and wound complications (odds ratio, 1.76; 95% confidence interval, 1.19–2.60, I 2 = 0%) compared with patients without obesity. Conversely, patients with obesity had lower rates of hypoparathyroidism (odds ratio, 0.79; 95% confidence interval, 0.71–0.88, I 2 = 0%). However, no difference was observed between groups regarding operative time (mean difference, 3.5 minutes; 95% confidence interval, −1.6, 8.7, I 2 = 95%) and length of hospital stay (mean difference, 0.3 days; 95% confidence interval, −0.2, 0.7, I 2 = 100%). Conclusion Despite having a lower risk of developing hypoparathyroidism, patients with obesity demonstrated increased risk for hematoma, recurrent laryngeal nerve injury, and wound complications. Nonetheless, further research exploring more stratified body mass index ranges and strategies to mitigate thyroidectomy complications is needed to ascertain the safety of patients with obesity undergoing thyroidectomy.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Clinical impact of obesity on thyroidectomy outcomes: A systematic review and meta-analysis
- Date Crossref
- 01/10/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University College Dublin pays non établi dans la noticeUniversité ou école supérieure
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Twitter (United States) pays non établi dans la noticeEntreprise
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University of Nicosia pays non établi dans la noticeUniversité ou école supérieure
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Cambridge University Hospitals NHS Foundation Trust pays non établi dans la noticeOrganisme public
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Mayo Clinic in Arizona Department of Surgery pays non établi dans la noticeÉtablissement de santé
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Cleveland Clinic pays non établi dans la noticeÉtablissement de santé
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School of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Integrated Surgical Institute Department of Endocrine Surgery pays non établi dans la noticeStructure de recherche
University College Dublin, Twitter (United States) et University of Nicosia, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.