Analysis of factors influencing mortality in immunocompetent children with severe adenovirus pneumonia undergoing conventional treatments: a retrospective cohort study
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Le résumé fourni par la source
Background: Severe adenovirus pneumonia (SAP) in immunocompetent children can progress rapidly despite conventional treatment, posing significant clinical challenges. The objective of this study to assess the factors influencing mortality in immunocompetent children with SAP undergoing conventional therapies. Early identification of risk factors for mortality is essential to guide timely intervention and optimize management strategies. Methods: In this study, we conducted a retrospective study of 156 immunocompetent pediatric patients diagnosed with SAP, who were divided into the conventional treatments survivor group and death group, without receiving extracorporeal membrane oxygenation (ECMO). Baseline clinical features, laboratory data, imaging findings, treatments and complications were collected. Patients were followed until discharge or death, with mortality confirmed from medical records. Results: ) (OR: 2.187, 95% CI: 1.079-4.434, P=0.03), and pulmonary consolidation affecting two or more lobes (OR: 9.071, 95% CI: 1.123-73.248, P=0.04). Conclusions: levels, and extent of lung consolidation in children with SAP undergoing conventional treatment. Recognizing these risk factors early may prompt consideration of advanced supportive therapies beyond conventional measures to improve survival outcomes.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Analysis of factors influencing mortality in immunocompetent children with severe adenovirus pneumonia undergoing conventional treatments: a retrospective cohort study
- Date Crossref
- 01/07/2025
- Éditeur
- AME Publishing Company
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Guangzhou Women and Children Medical Center pays non établi dans la noticeÉtablissement de santé
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First Affiliated Hospital of Jinan University pays non établi dans la noticeÉtablissement de santé
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Guangzhou Medical University Department of Pediatric Respiratory pays non établi dans la noticeUniversité ou école supérieure
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Southern Medical University pays non établi dans la noticeUniversité ou école supérieure
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Jinan University Department of Pediatrics pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health SL-3 Laboratory (Guangdong) pays non établi dans la noticeUniversité ou école supérieure
Guangzhou Women and Children Medical Center, First Affiliated Hospital of Jinan University et Department of Pediatric Respiratory — Guangzhou Medical University, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.