Comparison of Quality of Life in Transfemoral Amputee Using Bone‐Anchored Prostheses vs. Socket Prostheses: A Systemic Review and Meta‐Analysis

Résumé fourni par la source

Amputation has a profound impact on an individual's quality of life (QoL) and functional ability. While socket prostheses are the current first-line treatment, they often cause socket-related issues. Bone-anchored prostheses (BAP) have been introduced to address these problems and improve the amputee experience. This systematic review and meta-analysis aim to compare the QoL between bone-anchored and socket prostheses in transfemoral amputees. A systematic review and meta-analysis were conducted from November 2023 to July 2024, following PRISMA guidelines. Databases including PUBMED, EMBASE, Scopus, Cochrane, and Web of Science were searched. Studies of single-arm trial design comparing pre- and post-operative outcomes were selected based on specific inclusion and exclusion criteria. Statistical analysis was performed using inverse variance with a random effect model. The primary outcome was QoL, measured using the Questionnaire for Persons with a Transfemoral Amputation (Q-TFA) and 36-Item Short Form Survey (SF-36), and the secondary outcome was mobility, assessed by the 6-Minute Walk Test (6MWT). Subgroup analyses compared different types of BAP (Press-fit vs. Screw-type) on QoL. Thirteen NRCTs with 398 participants were included. Significant improvements in QoL were observed in all Q-TFA domains and the SF-36 Physical Component Score (PCS), but not in the SF-36 Mental Component Score (MCS). Mobility improved significantly as measured by the six-minute walk test (6MWT). No significant differences in QoL were found between Press-fit and Screw-type BAP implants. Overall, BAP significantly improve both QoL and mobility, but study limitations currently restrict their use to individuals with socket-related complications. As such, it cannot yet be universally recommended as a first-line intervention.

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