The potential diagnostic benefit of repeated troponin I measurements following high-intensity exercise
Rattachement africain : no. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
OBJECTIVES: Myocardial stress increases troponin levels after exercise in individuals with and without coronary artery disease. This study investigates whether maximal or prolonged high-intensity exercise affects post-exercise cardiac troponin I (cTnI) levels in well-trained individuals with stable revascularised coronary artery disease (Revasc-CAD) compared to those without obstructive coronary artery disease (Wo-CAD). DESIGN: Observational study. METHODS: CTnI levels were measured pre-, 3- and 24-h post-exercise in 15 middle-aged Revasc-CAD and 22 Wo-CAD individuals. Participants underwent a maximal cardiopulmonary exercise test and three high-intensity interval spinning sessions with increasing durations of 20, 40, and 60 min, at one-week intervals. RESULTS: Following exercise, cTnI levels peaked at 3 h, with significant reduction at 24 h (p < 0.001). The highest cTnI levels were observed after the 60-minute session (p = 0.001). There were no differences in cTnI levels between the two groups following high-intensity exercise or increased exercise duration. In contrast, there was no reduction in cTnI between 3 and 24 h after maximal exercise in the Revasc-CAD group. During the study, a progressive post-exercise cTnI elevation was observed following exercise in a participant with in-stent stenosis. He had normal resting cTnI levels but demonstrated increasing post-exercise cTnI during progression of the coronary artery obstruction. CONCLUSIONS: High-intensity exercise of varying durations caused similar cTnI elevations in Revacs-CAD and Wo-CAD groups, but maximal exercise resulted in prolonged cTnI elevation in Revasc-CAD individuals. Progressive post-exercise cTnI increases in a participant with in-stent restenosis highlight the potential value of repeated post-exercise cTnI assessments for detecting evolving coronary artery obstruction.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The potential diagnostic benefit of repeated troponin I measurements following high-intensity exercise
- Date Crossref
- 01/01/2026
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Stavanger University Hospital Department of Cardiology pays non établi dans la noticeÉtablissement de santé
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Hospital of Southern Norway pays non établi dans la noticeÉtablissement de santé
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Sørlandet Sykehus pays non établi dans la noticeÉtablissement de santé
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University of Stavanger Department of Electrical Engineering and Computer Science pays non établi dans la noticeUniversité ou école supérieure
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Oslo University Hospital pays non établi dans la noticeÉtablissement de santé
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Diakonhjemmet Hospital pays non établi dans la noticeÉtablissement de santé
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Sørlandet Hospital Kristiansand Department of Cardiology pays non établi dans la noticeÉtablissement de santé
Department of Cardiology — Stavanger University Hospital, Hospital of Southern Norway et Sørlandet Sykehus, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.