Innovative Regenerative Treatment with Nanofat Injection for Hypertensive Ischemic Leg Ulcer: A Case Report

Résumé fourni par la source

Background: Martorell's ulcer, also known as hypertensive ischemic leg ulcer (HYTILU) or Martorell hypertensive ischemic ulcer, presents significant therapeutic challenges. The regenerative potential of nanofat, derived from adipose tissue, offers a promising therapeutic option. Case Presentation: and persisting for more than 5 years. The patient had longstanding hypertension, controlled with three antihypertensive medications, and type 2 diabetes mellitus with microangiopathy. A single injection of 5 mL nanofat, prepared using the Tonnard technique, was administered intradermally at the wound site. Within 3 months, the ulcer surface reduced by 70%, achieving complete healing at 6 months. Pain management was significantly improved, with the visual analog scale (VAS) decreasing from 8/10 to 0/10 within 7 days. Quality of life, assessed using the Nottingham Health Profile and SCAR-Q, showed remarkable improvement. No adverse events were noted. Conclusion: This case shows how nanofat can promote quick healing, relieve pain, and improve quality of life in a chronic ischemic wound. It offers a safe, minimally invasive, and effective alternative to traditional treatments. More research is needed to validate these results.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.