Recurrent Urinary Tract Infection in Diabetics: A Retrospective Analysis
Rattachement africain : pk, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background Recurrent urinary tract infections (rUTIs) are a common complication in diabetic individuals due to impaired immune responses, poor glycemic control, and anatomical abnormalities. Objective Given the high burden of diabetes, rising antimicrobial resistance, and the paucity of local epidemiological data on recurrent UTIs in this population, this study aimed to determine the clinical characteristics, microbial profile, antibiotic resistance patterns, and associated risk factors of recurrent urinary tract infections in patients with diabetes mellitus. Methods This retrospective study was conducted at Fatima Memorial Hospital, Lahore, Pakistan from April 2023 to April 2025. A total of 320 patients with a confirmed diagnosis of diabetes and documented episodes of recurrent urinary tract infections were included in the study. Clinical and laboratory data were extracted from electronic and paper-based medical records using a standardized data collection form. Results The mean age of patients was 59.4 ± 11.2 years, with females comprising 218 (68.1%) of the cohort. Type 2 diabetes accounted for 286 (89.4%) of cases. Poor glycemic control (HbA1c > 7.5%) was observed in 229 (71.6%) of patients. The most common pathogen was E. coli (180, 56.3%), followed by Klebsiella pneumoniae (59, 18.4%) and Enterococcus faecalis (29, 9.1%). Multidrug resistance was noted in 146 (45.6%) of isolates; 118 (36.9%) were extended-spectrum beta-lactamases (ESBL) producers. Logistic regression identified female gender (OR: 2.84), poor glycemic control (OR: 3.12), diabetes duration >10 years (OR: 2.45), diabetic nephropathy (OR: 2.19), and prior UTI-related hospitalization (OR: 3.67) as significant predictors of recurrence and resistance (p < 0.05). Conclusion It is concluded that recurrent UTIs are common in diabetic patients and are significantly influenced by glycemic control, gender, disease duration, and renal complications. Rising antibiotic resistance among uropathogens necessitates routine culture-based treatment and individualized preventive strategies to improve outcomes in this high-risk group.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Recurrent Urinary Tract Infection in Diabetics: A Retrospective Analysis
- Date Crossref
- 13/07/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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GIFT University pays non établi dans la noticeUniversité ou école supérieure
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CMH Lahore Medical College and Institute of Dentistry pays non établi dans la noticeÉtablissement de santé
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Memorial Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
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Fatima Memorial Hospital pays non établi dans la noticeÉtablissement de santé
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Shalamar Hospital pays non établi dans la noticeÉtablissement de santé
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Ghazi University pays non établi dans la noticeUniversité ou école supérieure
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Allama Iqbal Medical College pays non établi dans la noticeUniversité ou école supérieure
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Internal Medicine pays non établi dans la noticeInstitution
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Abu Umara Medical and Dental College Pharmacology pays non établi dans la noticeUniversité ou école supérieure
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Avicenna Medical and Dental College Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Shalamar Medical & Dental College Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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District Headquarter (DHQ) Hospital Internal Medicine pays non établi dans la noticeÉtablissement de santé
GIFT University, CMH Lahore Medical College and Institute of Dentistry et Internal Medicine — Memorial Hospital, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.