A dosimetric study to evaluate the inverse planning simulated annealing (IPSA) and hybrid inverse planning optimization (HIPO) algorithms in HDR brachytherapy of cervical cancer
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Le résumé fourni par la source
PURPOSE: To compare the effectiveness of the inverse planning simulated annealing (IPSA) and hybrid inverse planning optimization (HIPO) algorithms in interstitial HDR brachytherapy for treatment of cervical cancer. METHODS AND MATERIALS: A dosimetric study was conducted on 46 cervical cancer patients who underwent multi catheter interstitial cervical HDR brachytherapy using the Martinez Universal Perineal Interstitial Template (MUPIT). Dosimetric parameters, plan evaluation indices, and mean treatment time were assessed for each algorithm. All the parameters were compared using statistical analysis. RESULTS: With HIPO, significant improvements were observed in D90, D100, V100, and V200 (P < 0.05). Additionally, HIPO plans demonstrated lower doses to the bladder (B2cc) as compared to IPSA plans, whereas IPSA plans exhibited lower rectum (R2cc) and sigmoid (S2cc) doses, with statistical significance observed only for sigmoid doses. HIPO plans had better results in the plan evaluation indices such as CI, COIN, DHI, DNR, ODI, EI, NV100, GFB, GFR, GF, PQI1, PQI2, and PQS with statistical significance (P < 0.05) except for GFS. Moreover, HIPO plans had shorter mean treatment time compared to IPSA plans by 5.52 seconds, although this difference did not reach statistical significance. It was found that HIPO plans demonstrated superior dose-volumetric parameters for the high-risk clinical target volume (HR-CTV). CONCLUSIONS: In conclusion, HIPO emerged as the preferred algorithm for interstitial cervical HDR brachytherapy due to improved dose distribution in HR-CTV and plan quality as well.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A dosimetric study to evaluate the inverse planning simulated annealing (IPSA) and hybrid inverse planning optimization (HIPO) algorithms in HDR brachytherapy of cervical cancer
- Date Crossref
- 01/04/2025
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Institute of Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Banaras Hindu University Department of Radiotherapy and Radiation Medicine pays non établi dans la noticeUniversité ou école supérieure
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Netaji Subhash Chandra Bose Medical College pays non établi dans la noticeÉtablissement de santé
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Cancer Institute (WIA) pays non établi dans la noticeÉtablissement de santé
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N.S.C.B Medical College Department of Radiotherapy pays non établi dans la noticeUniversité ou école supérieure
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Garud Cancer Hospital Department of Radiation Oncology pays non établi dans la noticeÉtablissement de santé
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Kalyan Singh Super Speciality Cancer Institute Department Radiation Oncology pays non établi dans la noticeStructure de recherche
Institute of Medical Sciences, Department of Radiotherapy and Radiation Medicine — Banaras Hindu University et Netaji Subhash Chandra Bose Medical College, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.