Formulation of Antibacterial Mouthwashes Based On an Aqueous Extract of the Leaves of Prosopis Africana (Guill. Et Perr.) Taub (Fabaceae)

Résumé fourni par la source

The aim of this work was to propose an antibacterial mouthwash formulation based on aqueous extracts of the leaves of Prosopis africana (Fabaceae) for maintaining oral hygiene. Three types of mouthwashes were formulated, incorporating the liquid extract, freeze-dried extract, and oven-dried liquid extract of Prosopis africana as the active ingredient. Quality control of the formulations involved the evaluation of macroscopic and organoleptic characteristics, pH, phytochemical composition, and in vitro antimicrobial activity. The mouthwashes were liquid in consistency, clear in appearance, homogeneously green in color, with a menthol odor and a sweet taste. The pH values ranged from 5.05?±?0.03 for the mouthwash formulated with the liquid extract, 5.24?±?0.1 for the mouthwash formulated with the oven-dried extract, and 5.18?±?0.01 for the mouthwash formulated with the freeze-dried extract. The formulations containing the liquid extract showed higher levels of phytochemical content. All formulated mouthwashes exhibited broad-spectrum antimicrobial activity against the tested oral pathogens.

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