Global burden of tuberculosis among adults aged 60 years and older, 1990-2021: Findings from the global burden of disease study 2021
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Le résumé fourni par la source
OBJECTIVES: Tuberculosis (TB) poses a significant threat to global public health, particularly, among elderly individuals. This study aimed to provide a comprehensive analysis of the patterns and temporal trends in the global disease burden of HIV-negative TB among adults aged ≥60 years from 1990 to 2021. METHODS: Data on incidence, deaths, and disability-adjusted life-years of TB, drug-susceptible TB, multidrug-resistant TB (MDR-TB), and extensively drug-resistant TB (XDR-TB) were obtained from the Global Burden of Disease 2021. Frontier analysis was carried out to pinpoint areas for enhancement and disparities among nations stratified by development level. The Bayesian age-period-cohort model was used to forecast disease burden trends through 2035. RESULTS: A decreasing trend in age-standardized incidence rate, age-standardized mortality rate, and disability-adjusted life-years rates for TB and drug-susceptible TB was observed among the elderly population worldwide, whereas an upward trend was noted for MDR-TB and XDR-TB. Frontier analyses revealed a potential for burden alleviation among diverse nations and regions, with high socio-demographic index nations, such as the Republic of Korea, showing higher disease burden than expected for their sociodemographic development. The Bayesian age-period-cohort model revealed that by 2035, the MDR-TB and XDR-TB burden will continue increasing in the elderly population. CONCLUSIONS: The increasing MDR-TB and XDR-TB burden in older individuals underscores the need for tailored interventions to combat TB burden, such as implementing active case finding among adults aged 60 years and older.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Global burden of tuberculosis among adults aged 60 years and older, 1990-2021: Findings from the global burden of disease study 2021
- Date Crossref
- 01/09/2025
- Éditeur
- Elsevier BV
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Harbin Medical University pays non établi dans la noticeUniversité ou école supérieure
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Heilongjiang Provincial Hospital pays non établi dans la noticeÉtablissement de santé
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Heilongjiang Center for Tuberculosis Control and Prevention pays non établi dans la noticeÉtablissement de santé
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School of Health Management Department of Social Medicine pays non établi dans la noticeUniversité ou école supérieure
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Infectious Disease Hospital of Heilongjiang Province pays non établi dans la noticeÉtablissement de santé
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Heilongjiang Center for Disease Control and Prevention pays non établi dans la noticeOrganisation à but non lucratif
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Heilongjiang Provincial Center for Disease Control and Prevention pays non établi dans la noticeOrganisation à but non lucratif
Harbin Medical University, Heilongjiang Provincial Hospital et Heilongjiang Center for Tuberculosis Control and Prevention, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.