Investigation of the Optimal Parameters for Block Sequential Regularized Expectation Maximization (BSREM) Reconstruction in Bone SPECT Using a Ring-type Semiconductor SPECT/CT

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PURPOSE: This research aims to optimize the block sequential regularized expectation maximization (BSREM) reconstruction in bone single photon emission computed tomography (SPECT) images using a ring-type SPECT/computed tomography (CT) system in terms of image quality and accuracy of quantitative evaluation. METHODS: ). Clinical images were reconstructed, and the reconstructions were evaluated as superior based on phantom results. RESULTS: compared to Anger type. Based on the phantom experiment, γ value 5.0, β values 0.5-0.9, and γ value 10, β values 0.7-0.9 were evaluated as superior. Clinical images under these reconstructions, determined from the phantom experiments, with γ value 5.0, β value 0.9, showed the smoothest of normal bone and the clearest separation of neighboring tumors. CONCLUSION: As reconstruction parameters for BSREM reconstruction in bone SPECT on a ring-type semiconductor SPECT/CT system, a γ value of 5.0 and a β value of 0.9 were considered suitable for image quality and quantitative evaluation.

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