Accès ouvert déclaré 2025 article

Pre-earthquake kidney function is a predictor of outcomes in earthquake-related crush syndrome

Ramazan Danış, Savaş Öztürk, Ismail Doruk Kocyigit, Jehat Kılıç, M. M. Civan, Tuncay Şahutoğlu, Di̇lek Torun, Engin Onan, Ahmet Alper KIYKIM, Şimal Köksal Cevher, Gürsel Yıldız, Zeynep Ebru Eser, Fatma Betül Güzel, Süleyman Karaköse, Tolga Yıldırım, Mehmet Polat, Ebru Gök Oğuz, Ali Gürel, Yasemin Coşkun Yavuz, Hasan KAYABAŞI, Zehra Eren, Mehmet Rıza Altıparmak, Nurhan Seyahi, Mehmet Küçüksu, Sibel Gökçay Bek, Esra Akçalı, İrem Pembegül, Zeki Aydın, Elif Arı, Saliha Yıldırım, Sabahat Alışır Ecder, Funda Sarı, Yavuz Ayar, Murat Tuğçu, Ayça İnci, Numan Görgülü, N. Yilmaz Selçuk, Gülizar Manga Şahin, Cuma Bülent Gul, Hamad Dheir, Özdem Kavraz Tomar, Abdülkadir Ünsal, Sedat Üstündağ, Ali Rıza Odabaş, Serhan Tuğlular

1Citations signalées, ce qui n’est pas une note de qualité

44Institutions déclarées

4Pays d’affiliation déclarés

Rattachement africain : tr, kh, ag, co. Niveau de preuve : code pays fourni par la source.

Le résumé fourni par la source

BACKGROUND: The devastating earthquakes in Kahramanmaraş, Türkiye, in February 2024, caused extensive trauma and loss of lives, causing unique challenges in the management of earthquake-related crush syndrome. The current study investigates the prognostic value of pre-earthquake kidney function for mortality prediction in patients diagnosed with crush syndrome. METHODS: A multi-center retrospective analysis was performed using data from 469 patients treated at 46 nephrology clinics. Pre-earthquake Kidney function, defined by serum creatinine and estimated glomerular filtration rate (eGFR) levels, was obtained from pre-earthquake health records. Clinical findings, laboratory parameters, complications, and survival probabilities were analyzed. Multivariate Cox regression was used to identify independent predictors of in-hospital mortality. RESULTS: The mean age of participants was 42.56 ± 16.92 years (Non-survivors: 50.46 ± 20.03 years, Survivors: 42.34 ± 16.80 years (p = 0.172)). The in-hospital mortality rate was 2.8%. Non-survivors exhibited significantly higher pre-earthquake creatinine levels than survivors (1.04 ± 0.61 mg/dL vs. 0.77 ± 0.33 mg/dL, p = 0.03), with lower eGFR (85.2 ± 34.7 mL/min/1.73 m² vs. 115.8 ± 39.4 mL/min/1.73 m², p = 0.008). Compared with survivors, non-survivors had higher incidences of AKI (92.3% vs. 61.6%, p = 0.037) and more severe metabolic disturbances, including hyperkalemia (5.41 ± 1.72 mmol/L vs. 5.13 ± 0.98 mmol/L, p = 0.008). Regression analysis revealed that pre-earthquake creatinine (HR: 9.121, 95% CI: 2.686-30.970, p < 0.001) and potassium levels at admission (HR: 3.338, 95% CI: 1.540-7.232, p = 0.002) were independent predictors of mortality. CONCLUSIONS: Pre-earthquake kidney function significantly predicts mortality in crush syndrome patients, highlighting the importance of baseline kidney assessment in disaster preparedness.

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Le contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref: Pre-earthquake kidney function is a predictor of outcomes in earthquake-related crush syndrome
Date Crossref: 08/06/2025
Éditeur: Springer Science and Business Media LLC
Type: journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.

Où se fait cette recherche

Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi pays non établi dans la notice
Établissement de santé
Istanbul University Department of Internal Medicine pays non établi dans la notice
Université ou école supérieure
Erciyes University Department of Internal Medicine pays non établi dans la notice
Université ou école supérieure
Kayseri Eğitim ve Araştırma Hastanesi pays non établi dans la notice
Établissement de santé
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi pays non établi dans la notice
Établissement de santé
Başkent University Department of Nephrology pays non établi dans la notice
Université ou école supérieure
Adana Hospital pays non établi dans la notice
Établissement de santé
Mersin Üniversitesi pays non établi dans la notice
Université ou école supérieure
Bilkent University pays non établi dans la notice
Université ou école supérieure
University of Health Science Department of Nephrology pays non établi dans la notice
Université ou école supérieure
Başkent University Hospital pays non établi dans la notice
Établissement de santé
Sağlık Bilimleri Üniversitesi pays non établi dans la notice
Université ou école supérieure

Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi, Department of Internal Medicine — Istanbul University et Department of Internal Medicine — Erciyes University, avec 9 autres affiliations.

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Les sujets associés

Muscle and Compartmental DisordersAbdominal Trauma and InjuriesAcute Kidney Injury Research

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