RELATIONSHIP BETWEEN AORTIC DIAMETERS AND CLINIC AND 24 HOURS BLOOD PRESSURE VALUES

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Objective: studies have suggested that even mild enlargement of the ascending aorta may predict the future occurrence of cardiovascular events. Therefore, dilatation of the ascending aorta may be considered as a form of preclinical vascular damage in hypertensive patients. Aim of our study: was to assess the correlation between clinic and 24 hours BP values and the dimensions of the aorta, measured at level of the sinuses of Valsalva (ValAO) and at the level of the proximal ascending aorta (AscAO) in subjects undergoing an echocardiogram at an ESH Excellence Centre for workup for suspect arterial hypertension. Design and method: 956 subjects (49% males, mean age 59±14 years, 72% hypertensives-HT) underwent an echocardiogram and clinic and 24 hours BP measurement and cardiac ultrasound. Results: Results: aortic diameters were greater HT as compared to NT (Val: 3.46±0.45 vs 3.29±0.48 cm, AscAo 3.35±0.46 vs 3.18±0.49, all p <0.001) and in males as compared to females (Val: 3.67±0.41 vs 3.15±0.36, AscAo 3.46±0.46 vs 3.13±0.42, all p <0.001). ValAO diameters Val were correlated to age (r 0.290, p<0.001), BMI (r 0.316, p<0.001) and to clinic and 24 hours blood pressure values (SBP r 0.109, 24 hrs SBP r 0.157, DBP r 0.098, 24hrsDBP r 0.166, all p<0.001). Similarly, AscAO diameters were correlated to age (r 0.415, p<0.001), BMI (r 0.325, p<0.001) and to clinic and 24 hours blood pressure values (SBP r 0.149, 24 hrs SBP r 0.124, DBP r 0.101, 24hoursDBP r 0.120 all p<0.001) (Steiger’s Z test p for the comparison of all correlation coefficients between different blood pressures ns) Conclusions: The dimensions of the proximal ascending aorta are significantly related to BP values. Aortic dimension are similarly related to clinic and to twenty-four hours BP values.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.