Accès ouvert déclaré
2025
article
Long-term exposure to fine particulate matter interacting with individual conditions increase breast cancer incidence: a large-scale Chinese cohort
Yue Sun, Xia Meng, Dong Sun, Dong Sun, Jianyi Zhao, Canqing Yu, Meng Zhu, Liang Shi, Ling Yang, Ling Yang, Yiping Chen, Huaidong Du, Hongbing Shen, Hongbing Shen, Jun Lv, Jun Lv, Haidong Kan, Qiang Ding, Dianjianyi Sun, the China Kadoorie Biobank Collaborative Group, Junshi Chen, Robert Clarke, Rory Collins, Yu Guo, Richard Peto, Robin Walters, Daniel Avery, Ruth Boxall, Derrick Bennett, Yumei Chang, Simon Gilbert, Alex Hacker, Mike Hill, Michael Holmes, Andri Iona, Christiana Kartsonaki, Rene Kerosi, Kong Ling, Om Kurmi, Garry Lancaster, Sarah Lewington, Kuang Lin, John McDonnell, Iona Millwood, Qunhua Nie, Jayakrishnan Radhakrishnan, Paul Ryder, Sam Sansome, Dan Schmidt, Paul Sherliker, Rajani Sohoni, Becky Stevens, Iain Turnbull, Jenny Wang, Xiaoming Yang, Neil Wright, Xiaoming Yang, Zheng Bian, Xiao Han, Chao Liu, Pei Pei, Chao Liu, Zengchang Pang, Ruqin Gao, Yongmei Liu, Shaojie Wang, Yongmei Liu, Ranran Du, Yajing Zang, Liang Cheng, Xiaocao Tian, Hua Zhang, Yaoming Zhai, Feng Ning, Xiaohui Sun, Feifei Li, Silu Lv, Junzheng Wang, Wei Hou, Mingyuan Zeng, Ge Jiang, Xue Zhou, Liqiu Yang, Hui He, Qinai Xu, Yanjie Li, Dan Wang, Ziyan Guo, Dan Wang, Yan Fu, Jinyan Chen, Yan Fu, Zhenwang Fu, Xiaohuan Wang, Min Weng, Zhendong Guo, Shukuan Wu, Yilei Li, Huimei Li, Zhifang Fu, Ming Wu, Yonglin Zhou, Jinyi Zhou, Ran Tao, Jie Yang, Jian Su, Fang Liu, Jun Zhang, Yihe Hu, Yan Lu, Liangcai Ma, Aiyu Tang, Shuo Zhang, Jianrong Jin, Jingchao Liu, Zhenzhu Tang, Naying Chen, Ying Huang, Mingqiang Li, Jinhuai Meng, Jian Lan, Qilian Jiang, Jian Lan, Yun Liu, Liuping Wei, Liyuan Zhou, Ningyu Chen Ping Wang, Fanwen Meng, Yulu Qin, Sisi Wang, Xianping Wu, Ningmei Zhang, Xiaofang Chen, Weiwei Zhou, Guojin Luo, Jianguo Li, Xunfu Zhong, Jiaqiu Liu, Qiang Sun, Pengfei Ge, Xiaolan Ren, Caixia Dong, Hui Zhang, Enke Mao, Xi Zhang, Tao Wang, Xi Zhang, Ding Zhang, Gang Zhou, Shixian Feng, Liang Chang, Lei Fan, Yulian Gao, Pan He, Huarong Sun, Pan He, Huifang Wu, Xukui Zhang, Canqing Yu, Min Yu, Ruying Hu, Chunmei Wang, Yijian Qian, Chunmei Wang, Kaixu Xie, Lingli Chen, Yidan Zhang, Dongxia Pan, Qijun Gu, Yuelong Huang, Biyun Chen, Li Yin, Huilin Liu, Xin Xu, Qiaohua Xu, Xin Xu, Hao Zhang, Huajun Long, Xianzhi Li, Libo Zhang, Zhe Qiu
2Citations signalées — pas une note de qualité
5Institutions déclarées
3Pays d’affiliation déclarés
Résumé fourni par la source
Breast cancer is the most frequently diagnosed malignancy among women worldwide. This study aimed to investigate the impact of long-term fine particulate matter (PM 2.5 ) exposure on breast cancer incidence in a cohort of 281,152 women from the China Kadoorie Biobank who were initially free of breast cancer. PM 2.5 concentrations were estimated using a high-resolution satellite-based model, and breast cancer cases were ascertained through national databases. Over a median follow-up of 11.12 years, 2393 new breast cancer cases were reported. Analyses using Cox proportional hazard and restricted cubic spline models demonstrated a non-linear association between PM 2.5 exposure and breast cancer incidence, with a marked increase in risk observed once PM 2.5 surpassed 53.6 μg/m 3 . For every 10 μg/m 3 increase in PM 2.5 , the hazard ratio for breast cancer incidence was 1.07 (95% confidence interval: 1.03–1.12). Furthermore, interactions were noted between PM 2.5 , physical activity, and life satisfaction, indicating that high pollution levels may diminish the protective benefits of exercise and positive psychological well-being. These findings highlight the need for stringent air pollution control measures and underscore the importance of integrated strategies that consider environmental, lifestyle, and psychological factors to reduce the burden of breast cancer.
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Contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Long-term exposure to fine particulate matter interacting with individual conditions increase breast cancer incidence: a large-scale Chinese cohort
- Date Crossref
- 26/04/2025
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.
Institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.
Sujets associés
Air Quality and Health ImpactsClimate Change and Health ImpactsCancer Risks and Factors